The formation and accumulation of methylglyoxal (MGO), a highly reactive dicarbonyl
compound, has been implicated in the pathogenesis of type 2 diabetes, vascular …

Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of
reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed …

Atherosclerosis is one of the main complications of diabetes involving multiple causative
factors. Dysfunction of the vascular endothelium is a hallmark of most conditions that are …

Aldehydes are electrophilic compounds to which humans are pervasively exposed. Despite
a significant health risk due to exposure, the mechanisms of aldehyde toxicity are poorly …

Vitamin C in humans must be ingested for survival. Vitamin C is an electron donor, and this
property accounts for all its known functions. As an electron donor, vitamin C is a potent …

The formation and accumulation of advanced glycation endproducts (AGEs) are related to
diabetes and other age-related diseases. Methylglyoxal (MGO), a highly reactive dicarbonyl …

Carbonylation of proteins is an irreversible oxidative damage, often leading to a loss of
protein function, which is considered a widespread indicator of severe oxidative damage …

OBJECTIVE: Advanced glycoxidation end products (AGEs), the derivatives of glucose-
protein or glucose-lipid interactions, are implicated in the complications of diabetes and …

Reactive carbonyl compounds (RCCs) formed during lipid peroxidation and sugar
glycoxidation, namely Advanced lipid peroxidation end products (ALEs) and Advanced …

Aldehydes are organic compounds that are widespread in nature. They can be formed
endogenously by lipid peroxidation (LPO), carbohydrate or metabolism ascorbate …