A global catalog of whole-genome diversity from 233 primate species
The rich diversity of morphology and behavior displayed across primate species provides an
informative context in which to study the impact of genomic diversity on fundamental …
informative context in which to study the impact of genomic diversity on fundamental …
TMPRSS2 polymorphism (rs12329760) and the severity of the COVID-19 in Iranian population
A Yaghoobi, JS Lord, JS Rezaiezadeh… - PLoS …, 2023 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been responsible for
the recent pandemic since early 2020. Due to the wide range of clinical symptoms of this …
the recent pandemic since early 2020. Due to the wide range of clinical symptoms of this …
Polymorphisms and mutations of ACE2 and TMPRSS2 genes are associated with COVID-19: a systematic review
J Li, Y Wang, Y Liu, Z Zhang, Y Zhai, Y Dai… - European Journal of …, 2022 - Springer
Objective To determine the effect of polymorphisms and mutations in angiotensin-converting
enzyme 2 (ACE2) and Type 2 transmembrane serine proteases (TMPRSS2) genes on …
enzyme 2 (ACE2) and Type 2 transmembrane serine proteases (TMPRSS2) genes on …
[HTML][HTML] Potential genes associated with COVID-19 and comorbidity
S Feng, F Song, W Guo, J Tan, X Zhang… - … journal of medical …, 2022 - ncbi.nlm.nih.gov
Hypertension, diabetes mellitus, and coronary artery disease are common comorbidities and
dangerous factors for infection and serious COVID-19. Polymorphisms in genes associated …
dangerous factors for infection and serious COVID-19. Polymorphisms in genes associated …
Viral and host genetic and epigenetic biomarkers related to SARS-CoV-2 cell entry, infection rate, and disease severity
J Gaspersic, V Dolzan - Biology, 2022 - mdpi.com
Simple Summary COVID-19 emerged as a new disease with quick transmission and a high
mortality rate at the end of 2019, caused by SARS-CoV-2. Common features of the …
mortality rate at the end of 2019, caused by SARS-CoV-2. Common features of the …
[HTML][HTML] Polymorphism of tmprss2 (rs12329760) but not ace2 (rs4240157), tmprss11a (rs353163) and cd147 (rs8259) is associated with the severity of COVID-19 in …
O Izmailova, O Shlykova, A Kabaliei… - Acta Bio Medica …, 2023 - ncbi.nlm.nih.gov
Methods: The study population consisted of the Ukrainian population with COVID-19:
patients without oxygen therapy (n= 62), with non-invasive (n= 92) and invasive (n= 35) …
patients without oxygen therapy (n= 62), with non-invasive (n= 92) and invasive (n= 35) …
In plain sight: the role of alpha-1-antitrypsin in COVID-19 pathogenesis and therapeutics.
KY Oguntuyo, CS Stevens, MN Siddiquey… - Biorxiv: the Preprint …, 2020 - europepmc.org
Entry of SARS-CoV-2 is facilitated by endogenous and exogenous proteases. These
proteases proteolytically activate the SARS-CoV-2 spike glycoprotein and are key …
proteases proteolytically activate the SARS-CoV-2 spike glycoprotein and are key …
Distinct evolutionary trajectories of SARS-CoV-2-interacting proteins in bats and primates identify important host determinants of COVID-19
The coronavirus disease 19 (COVID-19) pandemic is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), a coronavirus that spilled over from the bat …
syndrome coronavirus 2 (SARS-CoV-2), a coronavirus that spilled over from the bat …
The fatal contribution of serine protease-related genetic variants to COVID-19 outcomes
LE Martínez-Gómez, C Martinez-Armenta… - Frontiers in …, 2024 - frontiersin.org
Introduction Serine proteases play a critical role during SARS-CoV-2 infection. Therefore,
polymorphisms of transmembrane protease serine 2 (TMPRSS2) and serpine family E …
polymorphisms of transmembrane protease serine 2 (TMPRSS2) and serpine family E …
[HTML][HTML] ACE2 and TMPRSS2 polymorphisms and the development of COVID-19: A review of the literature
AA da Silva Oliveira, AMP da Silva… - … Journal of Clinical …, 2022 - clinvirologyjournal.com
SARS-CoV-2 is a virus that has a positive-sense, single-stranded RNA genome that
encodes 4 structural proteins, the main one being the S protein (Spike) responsible for …
encodes 4 structural proteins, the main one being the S protein (Spike) responsible for …