Monomolecular arrays of protein or glycoprotein subunits forming surface layers (S-layers)
are one of the most commonly observed prokaryotic cell envelope components. S-layers are …

The metabolism of Archaea, the third domain of life, resembles in its complexity those of
Bacteria and lower Eukarya. However, this metabolic complexity in Archaea is accompanied …

Post-translational modifications define the functional and structural plasticity of proteins in
archaea, prokaryotes and eukaryotes. Multi-site protein modification modulates protein …

Binuclear metallohydrolases are a structurally diverse group of enzymes that use binuclear
metal ion centers to catalyze the hydrolysis of amides and esters of carboxylic and …

SUMMARY N-glycosylation of proteins is one of the most prevalent posttranslational
modifications in nature. Accordingly, a pathway with shared commonalities is found in all …

Asparagine-linked glycosylation involves the sequential assembly of an oligosaccharide
onto a polyisoprenyl donor, followed by the en bloc transfer of the glycan to particular …

Glycosylation of proteins is one of the most prevalent post-translational modifications
occurring in nature, with a wide repertoire of biological implications. Pathways for the main …

Most prokaryotic cells are encased in a surface layer (S-layer) consisting of a paracrystalline
array of repeating lattice-forming proteins. S-layer proteins populate a vast and diverse …

The genomes of all organisms throughout the tree of life are compacted and organized in
chromatin by association of chromatin proteins. Eukaryotic genomes encode histones, which …

Terpenoids, also known as isoprenoids, are the largest and most diverse class of organic
compounds in nature and are involved in many membrane-associated cellular processes …