The frontiers of bioimaging are currently being pushed toward the integration and correlation
of several modalities to tackle biomedical research questions holistically and across multiple …

Imaging is one of the key technologies underpinning discoveries in biomedical research.
Each imaging technique however usually only provides a specific type of information. For …

Technical improvements in electron microscopy, both instrumental and preparative, permit
increasingly accurate analyses. Digital images for transmission electron microscopy (TEM) …

The infection course of Mycobacterium tuberculosis is highly dynamic and comprises
sequential stages that require damaging and crossing of several membranes to enable the …

Identifying endogenous tissue stem cells remains a key challenge in developmental and
regenerative biology. To distinguish and molecularly characterise stem cell populations in …

Fiducial-based correlation of fluorescence and electron microscopy data from high-pressure
frozen and resin-embedded samples allows for high-precision localization of fluorescent …

Chloride is the most abundant inorganic anions in almost all cells and in human circulation
systems. Its homeostasis is therefore important for systems physiology and normal cellular …

Synthetic cells are artificial systems that resemble natural cells. Significant efforts have been
made over the years to construct synthetic protocells that can mimic biological mechanisms …

Correlating complementary multiple scale images of the same object is a straightforward
means to decipher biological processes. Light microscopy and electron microscopy are the …

The endocytic pathway is composed of distinct types of endosomes that vary in shape,
function, and molecular composition. In addition, endosomes are highly dynamic structures …