4004 ESC Guidelines label use of medication should be limited to situations where it is in
the patient's interest to do so, with regard to the quality, safety, and efficacy of care, and only …

The recommendations listed in this clinical practice guideline are, whenever possible,
evidence-based. An initial extensive evidence review, which included literature derived from …

Sudden cardiac death (SCD) from cardiac arrest is a major international public health
problem accounting for an estimated 15%–20% of all deaths. Although resuscitation rates …

Conduction disorders and arrhythmias remain difficult to treat and are increasingly prevalent
owing to the increasing age and body mass of the general population, because both are risk …

Ischemic heart disease is the greatest health burden and most frequent cause of death
worldwide. Myocardial ischemia/reperfusion is the pathophysiological substrate of ischemic …

Ventricular arrhythmia and subsequent sudden cardiac death (SCD) due to acute
myocardial infarction (AMI) is one of the most frequent causes of death in humans. Lethal …

Sudden cardiac death (SCD) is responsible for several millions of deaths every year and
remains a major health problem. To reduce this burden, diagnosing and identification of …

Genetic conditions, even those associated with identical gene mutations, can present with
variable clinical manifestations. One widely accepted explanation for this phenomenon is …

Background: Persistent severe left ventricular (LV) systolic dysfunction after myocardial
infarction (MI) is associated with increased mortality and is a class I indication for …

The overall incidence of sudden cardiac death is considerably lower among women than
men, reflecting significant and often under-recognized sex differences. Women are older at …