How to characterize the function of a brain region

S Genon, A Reid, R Langner, K Amunts… - Trends in cognitive …, 2018 - cell.com
Many brain regions have been defined, but a comprehensive formalization of each region's
function in relation to human behavior is still lacking. Current knowledge comes from various …

Cholinergic modulation of spatial learning, memory and navigation

N Solari, B Hangya - European Journal of Neuroscience, 2018 - Wiley Online Library
Spatial learning, including encoding and retrieval of spatial memories as well as holding
spatial information in working memory generally serving navigation under a broad range of …

Egocentric boundary vector tuning of the retrosplenial cortex

AS Alexander, LC Carstensen, JR Hinman… - Science …, 2020 - science.org
The retrosplenial cortex is reciprocally connected with multiple structures implicated in
spatial cognition, and damage to the region itself produces numerous spatial impairments …

The retrosplenial-parietal network and reference frame coordination for spatial navigation.

BJ Clark, CM Simmons, LE Berkowitz… - Behavioral …, 2018 - psycnet.apa.org
The retrosplenial cortex is anatomically positioned to integrate sensory, motor, and visual
information and is thought to have an important role in processing spatial information and …

What about “space” is important for episodic memory?

CL Fan, HM Sokolowski… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Early cognitive neuroscientific research revealed that the hippocampus is crucial for spatial
navigation in rodents, and for autobiographical episodic memory in humans. Researchers …

[HTML][HTML] The neuroscience of spatial navigation and the relationship to artificial intelligence

E Bermudez-Contreras, BJ Clark… - Frontiers in Computational …, 2020 - frontiersin.org
Recent advances in artificial intelligence (AI) and neuroscience are impressive. In AI, this
includes the development of computer programs that can beat a grandmaster at GO or …

Impaired hippocampal-cortical interactions during sleep in a mouse model of Alzheimer's disease

SD Cushing, I Skelin, SC Moseley, AC Stimmell… - Current Biology, 2020 - cell.com
Spatial learning is impaired in humans with preclinical Alzheimer's disease (AD). We
reported similar impairments in 3xTg-AD mice learning a spatial reorientation task. Memory …

Scalp recorded theta activity is modulated by reward, direction, and speed during virtual navigation in freely moving humans

MH Lin, O Liran, N Bauer, TE Baker - Scientific reports, 2022 - nature.com
Abstract Theta oscillations (~ 4–12 Hz) are dynamically modulated by speed and direction in
freely moving animals. However, due to the paucity of electrophysiological recordings of …

Using virtual global landmark to improve incidental spatial learning

J Liu, AK Singh, CT Lin - Scientific reports, 2022 - nature.com
To reduce the decline of spatial cognitive skills caused by the increasing use of automated
GPS navigation, the virtual global landmark (VGL) system is proposed to help people …

Flexible egocentric and allocentric representations of heading signals in parietal cortex

X Chen, GC DeAngelis… - Proceedings of the …, 2018 - National Acad Sciences
By systematically manipulating head position relative to the body and eye position relative to
the head, previous studies have shown that vestibular tuning curves of neurons in the …