Perioperative events influence cancer recurrence risk after surgery

JG Hiller, NJ Perry, G Poulogiannis, B Riedel… - Nature reviews Clinical …, 2018 - nature.com
Surgery is a mainstay treatment for patients with solid tumours. However, despite surgical
resection with a curative intent and numerous advances in the effectiveness of (neo) …

Essential elements of multimodal analgesia in enhanced recovery after surgery (ERAS) guidelines

A Beverly, AD Kaye, O Ljungqvist… - Anesthesiology …, 2017 - anesthesiology.theclinics.com
Enhanced Recovery After Surgery (ERAS) Society guidelines provide an evidencebased,
multimodal approach to surgical care, to improve outcomes after major operations. The main …

The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy

JA Krall, F Reinhardt, OA Mercury… - Science translational …, 2018 - science.org
Patients undergoing surgical resection of primary breast tumors confront a risk for metastatic
recurrence that peaks sharply 12 to 18 months after surgery. The cause of early metastatic …

[HTML][HTML] The neutrophil-to-lymphocyte ratio: a narrative review

SS Faria, PC Fernandes Jr, MJB Silva… - …, 2016 - ncbi.nlm.nih.gov
Cellular-mediated inflammatory response, lymphocytes, neutrophils, and monocytes are
increasingly being recognised as having an important role in tumorigenesis and …

[HTML][HTML] Influence of perioperative anaesthetic and analgesic interventions on oncological outcomes: a narrative review

T Wall, A Sherwin, D Ma, DJ Buggy - British journal of anaesthesia, 2019 - Elsevier
Surgery is an important treatment modality for the majority of solid organ cancers.
Unfortunately, cancer recurrence following surgery of curative intent is common, and …

Potential impact of invasive surgical procedures on primary tumor growth and metastasis

M Alieva, J van Rheenen, MLD Broekman - Clinical & experimental …, 2018 - Springer
Surgical procedures such as tumor resection and biopsy are still the gold standard for
diagnosis and (determination of) treatment of solid tumors, and are prognostically beneficial …

DDX3 modulates cisplatin resistance in OSCC through ALKBH5-mediated m6A-demethylation of FOXM1 and NANOG

O Shriwas, M Priyadarshini, SK Samal, R Rath… - Apoptosis, 2020 - Springer
Platinum based drugs alone or in combination with 5FU and docetaxel are common regimen
chemotherapeutics for the treatment of advanced OSCC. Chemoresistance is one of the …

The wound inflammatory response exacerbates growth of pre‐neoplastic cells and progression to cancer

N Antonio, ML Bønnelykke‐Behrndtz, LC Ward… - The EMBO …, 2015 - embopress.org
There is a long‐standing association between wound healing and cancer, with cancer often
described as a “wound that does not heal”. However, little is known about how wounding …

The role of multimodal analgesia in pain management after ambulatory surgery

OL Elvir-Lazo, PF White - Current Opinion in Anesthesiology, 2010 - journals.lww.com
This article discusses recent evidence from the peer-reviewed literature regarding the role of
local anesthetics, NSAIDs, gabapentinoids, and acetaminophen, as well as alpha-2 …

Perioperative anesthesia care and tumor progression

MW Sekandarzad, AAJ van Zundert, PB Lirk… - Anesthesia & …, 2017 - journals.lww.com
IMMUNE PATHOGENESIS The principal line of defense against cancer cell invasion and
metastasis is established via the host's innate and adaptive immune response. The key …