Considerable progress has been made in the prevention, diagnosis, and management of
pediatric patients with invasive fungal disease (IFD). The reported decreasing trend in the …

This review compares the pharmacology, spectrum of antifungal activity, pharmacokinetic
and pharmacodynamic properties, safety and clinical efficacy of the three licensed …

Caspase recruitment domain–containing protein 9 (CARD9) is an adaptor molecule in the
cytosol of myeloid cells, required for induction of T-helper cells producing interleukin-17 …

Background: Candida is the third most common cause of late-onset neonatal sepsis in
infants born at< 1500 g. Candida parapsilosis infections are increasingly reported in preterm …

Background. Candida species are the leading cause of invasive fungal infections in
hospitalized children and are the third most common isolates recovered from patients with …

Invasive fungal infections, accompanied by high rates of mortality, represent an increasing
problem in medicine. Neutrophils are the major effector immune cells in fungal killing. Based …

The incidence of candidemia has been on a rise worldwide. The epidemiology of invasive
fungal infections in general and of candidemia in particular has changed in the past three …

ABSTRACT A 13-month prospective multicenter study including 44 hospitals was carried out
to evaluate the epidemiology of Candida parapsilosis complex candidemia in Spain …

Aim During the last decade a continuous increase in non‐albicans species isolation has
been observed with Candida parapsilosis being one of the leading species. Aim of this study …

Patients with haematological malignancies, haemopoietic stem cell transplant recipients and
patients requiring admission to intensive care settings are at high risk for invasive …