Computation through neural population dynamics

S Vyas, MD Golub, D Sussillo… - Annual review of …, 2020 - annualreviews.org
Significant experimental, computational, and theoretical work has identified rich structure
within the coordinated activity of interconnected neural populations. An emerging challenge …

Perspectives on classical controversies about the motor cortex

M Omrani, MT Kaufman… - Journal of …, 2017 - journals.physiology.org
Primary motor cortex has been studied for more than a century, yet a consensus on its
functional contribution to movement control is still out of reach. In particular, there remains …

Long-term stability of cortical population dynamics underlying consistent behavior

JA Gallego, MG Perich, RH Chowdhury, SA Solla… - Nature …, 2020 - nature.com
Animals readily execute learned behaviors in a consistent manner over long periods of time,
and yet no equally stable neural correlate has been demonstrated. How does the cortex …

A neural population mechanism for rapid learning

MG Perich, JA Gallego, LE Miller - Neuron, 2018 - cell.com
Long-term learning of language, mathematics, and motor skills likely requires cortical
plasticity, but behavior often requires much faster changes, sometimes even after single …

A systematic review on muscle synergies: from building blocks of motor behavior to a neurorehabilitation tool

RE Singh, K Iqbal, G White… - Applied bionics and …, 2018 - Wiley Online Library
The central nervous system (CNS) is believed to utilize specific predefined modules, called
muscle synergies (MS), to accomplish a motor task. Yet questions persist about how the …

Learning leaves a memory trace in motor cortex

DM Losey, JA Hennig, ER Oby, MD Golub, PT Sadtler… - Current Biology, 2024 - cell.com
How are we able to learn new behaviors without disrupting previously learned ones? To
understand how the brain achieves this, we used a brain-computer interface (BCI) learning …

Differential representation of articulatory gestures and phonemes in precentral and inferior frontal gyri

EM Mugler, MC Tate, K Livescu… - Journal of …, 2018 - Soc Neuroscience
Speech is a critical form of human communication and is central to our daily lives. Yet,
despite decades of study, an understanding of the fundamental neural control of speech …

Long-latency reflexes account for limb biomechanics through several supraspinal pathways

IL Kurtzer - Frontiers in integrative neuroscience, 2015 - frontiersin.org
Accurate control of body posture is enforced by a multitude of corrective actions operating
over a range of time scales. The earliest correction is the short-latency reflex (SLR) which …

Brain motor network changes in Parkinson's disease: Evidence from meta‐analytic modeling

DM Herz, D Meder, JA Camilleri, SB Eickhoff… - Movement …, 2021 - Wiley Online Library
Background Motor‐related brain activity in Parkinson's disease has been investigated in a
multitude of functional neuroimaging studies, which often yielded apparently conflicting …

Independent representations of ipsilateral and contralateral limbs in primary motor cortex

EA Heming, KP Cross, T Takei, DJ Cook, SH Scott - Elife, 2019 - elifesciences.org
Several lines of research demonstrate that primary motor cortex (M1) is principally involved
in controlling the contralateral side of the body. However, M1 activity has been correlated …