The critical role of social interactions in driving phenotypic variation has long been inferred
from the association between early social deprivation and adverse neurodevelopmental …

The brain's life-long capacity for experience-dependent plasticity allows adaptation to new
environments or to changes in the environment, and to changes in internal brain states such …

Transplantation of neural progenitor cells (NPC) is a promising therapeutic strategy for
replacing neurons lost after spinal cord injury, but significant challenges remain regarding …

We investigated how experience regulates the structure of a defined neuronal circuit in adult
mice. Enriched environment (EE) produced a robust and reversible increase in hippocampal …

Learning is correlated with the assembly of new synapses, but the roles of synaptogenesis
processes in memory are poorly understood. Here, we show that mice lacking β-Adducin fail …

Longitudinal studies in humans demonstrate the association between prenatal and
postnatal experiences of adversity and long-term changes in neurodevelopment. These …

Dendritic spines are the postsynaptic sites of the majority of excitatory synapses in the
mammalian central nervous system. The morphology and dynamics of dendritic spines …

Spinal cord injury research has greatly expanded in recent years, but our understanding of
the mechanisms that underlie the functional recovery that can occur over the weeks and …

Functional recovery after cortical injury, such as stroke, is associated with neural circuit
reorganization, but the underlying mechanisms and efficacy of therapeutic interventions …

Spinal cord injury (SCI) often results in the development of neuropathic pain, which can
persist for months and years after injury. Although many aberrant changes to sensory …