Rhythms of life: circadian disruption and brain disorders across the lifespan

RW Logan, CA McClung - Nature Reviews Neuroscience, 2019 - nature.com
Many processes in the human body—including brain function—are regulated over the 24-
hour cycle, and there are strong associations between disrupted circadian rhythms (for …

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium

IG McKeith, BF Boeve, DW Dickson, G Halliday… - Neurology, 2017 - AAN Enterprises
The Dementia with Lewy Bodies (DLB) Consortium has refined its recommendations about
the clinical and pathologic diagnosis of DLB, updating the previous report, which has been …

Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study

RB Postuma, A Iranzo, M Hu, B Högl, BF Boeve… - Brain, 2019 - academic.oup.com
Idiopathic REM sleep behaviour disorder (iRBD) is a powerful early sign of Parkinson's
disease, dementia with Lewy bodies, and multiple system atrophy. This provides an …

Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies

M Rossi, N Candelise, S Baiardi, S Capellari… - Acta …, 2020 - Springer
The clinical diagnosis of synucleinopathies, including Parkinson's disease (PD), dementia
with Lewy bodies (DLB), and multiple system atrophy (MSA), is challenging, especially at an …

Sleep health: an opportunity for public health to address health equity

L Hale, W Troxel, DJ Buysse - Annual review of public health, 2020 - annualreviews.org
The concept of sleep health provides a positive holistic framing of multiple sleep
characteristics, including sleep duration, continuity, timing, alertness, and satisfaction. Sleep …

REM sleep behaviour disorder

Y Dauvilliers, CH Schenck, RB Postuma… - Nature reviews Disease …, 2018 - nature.com
Rapid eye movement (REM) sleep behaviour disorder (RBD) is a parasomnia that is
characterized by loss of muscle atonia during REM sleep (known as REM sleep without …

Diagnostic value of cerebrospinal fluid alpha-synuclein seed quantification in synucleinopathies

I Poggiolini, V Gupta, M Lawton, S Lee, A El-Turabi… - Brain, 2022 - academic.oup.com
Several studies have confirmed the α-synuclein real-time quaking-induced conversion (RT-
QuIC) assay to have high sensitivity and specificity for Parkinson's disease. However …

MDS research criteria for prodromal Parkinson's disease

D Berg, RB Postuma, CH Adler, BR Bloem… - Movement …, 2015 - Wiley Online Library
This article describes research criteria and probability methodology for the diagnosis of
prodromal PD. Prodromal disease refers to the stage wherein early symptoms or signs of PD …

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

JA Obeso, M Stamelou, CG Goetz, W Poewe… - Movement …, 2017 - Wiley Online Library
This article reviews and summarizes 200 years of Parkinson's disease. It comprises a
relevant history of Dr. James Parkinson's himself and what he described accurately and …

[HTML][HTML] Clinical and imaging evidence of brain-first and body-first Parkinson's disease

J Horsager, K Knudsen, M Sommerauer - Neurobiology of disease, 2022 - Elsevier
Braak's hypothesis has been extremely influential over the last two decades. However,
neuropathological and clinical evidence suggest that the model does not conform to all …