The dental plaque biofilm matrix

NS Jakubovics, SD Goodman… - Periodontology …, 2021 - Wiley Online Library
The extracellular matrix is a critical component of microbial biofilms, such as dental plaque,
maintaining the spatial arrangement of cells and coordinating cellular functions throughout …

Extracellular DNA (eDNA). A major ubiquitous element of the bacterial biofilm architecture

D Campoccia, L Montanaro, CR Arciola - International Journal of …, 2021 - mdpi.com
After the first ancient studies on microbial slime (the name by which the biofilm matrix was
initially indicated), multitudes of studies on the morphology, composition and physiology of …

In situ targeted base editing of bacteria in the mouse gut

AK Brödel, LH Charpenay, M Galtier, FJ Fuche… - Nature, 2024 - nature.com
Microbiome research is now demonstrating a growing number of bacterial strains and genes
that affect our health. Although CRISPR-derived tools have shown great success in editing …

Microbiome or infections: amyloid-containing biofilms as a trigger for complex human diseases

AL Miller, S Bessho, K Grando, Ç Tükel - Frontiers in Immunology, 2021 - frontiersin.org
The human microbiota is the community of microorganisms that live upon or within their
human host. The microbiota consists of various microorganisms including bacteria, fungi …

Environmental exposures and autoimmune diseases: contribution of gut microbiome

MF Khan, H Wang - Frontiers in immunology, 2020 - frontiersin.org
Environmental agents have been gaining more attention in recent years for their role in the
pathogenesis of autoimmune diseases (ADs). Increasing evidence has linked environmental …

Curli-containing enteric biofilms inside and out: matrix composition, immune recognition, and disease implications

SA Tursi, Ç Tükel - Microbiology and Molecular Biology Reviews, 2018 - Am Soc Microbiol
Biofilms of enteric bacteria are highly complex, with multiple components that interact to
fortify the biofilm matrix. Within biofilms of enteric bacteria such as Escherichia coli and …

Lung endothelium, tau, and amyloids in health and disease

R Balczon, MT Lin, S Voth, AR Nelson… - Physiological …, 2024 - journals.physiology.org
Lung endothelia in the arteries, capillaries, and veins are heterogeneous in structure and
function. Lung capillaries in particular represent a unique vascular niche, with a thin yet …

Macrophage toll-like receptor 9 contributes to chemotherapy-induced neuropathic pain in male mice

X Luo, Y Huh, S Bang, Q He, L Zhang… - Journal of …, 2019 - Soc Neuroscience
Chemotherapy-induced peripheral neuropathy (CIPN) remains a pressing clinical problem;
however, our understanding of sexual dimorphism in CIPN remains unclear. Emerging …

CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-α production in systemic sclerosis

R Lande, EY Lee, R Palazzo, B Marinari… - Nature …, 2019 - nature.com
Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by fibrosis and
vasculopathy. CXCL4 represents an early serum biomarker of severe SSc and likely …

Abnormalities of the type I interferon signaling pathway in lupus autoimmunity

S Gallucci, S Meka, AM Gamero - Cytokine, 2021 - Elsevier
Type I interferons (IFNs), mostly IFNα and IFNβ, and the type I IFN Signature are important in
the pathogenesis of Systemic Lupus Erythematosus (SLE), an autoimmune chronic …