Emerging affinity ligands and support materials for the enrichment of monoclonal antibodies
Monoclonal antibodies (mAbs) have been served as 'magic bullet'to treat autoimmune
diseases, cancers, and infectious diseases. Due to the complexity of biological sample and …
diseases, cancers, and infectious diseases. Due to the complexity of biological sample and …
Bioanalytical methods for therapeutic monoclonal antibodies and antibody–drug conjugates: A review of recent advances and future perspectives
K Todoroki, H Mizuno, E Sugiyama… - Journal of Pharmaceutical …, 2020 - Elsevier
As the use and development of therapeutic monoclonal antibodies (mAbs) and antibody–
drug conjugates (ADCs) increases, the need for accurate and robust bioanalytical methods …
drug conjugates (ADCs) increases, the need for accurate and robust bioanalytical methods …
2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH …
S Kaur, SC Alley, M Szapacs, A Wilson, E Ciccimaro… - Bioanalysis, 2022 - Taylor & Francis
The 15th edition of the Workshop on Recent Issues in Bioanalysis (15th WRIB) was held on
27 September to 1 October 2021. Even with a last-minute move from in-person to virtual, an …
27 September to 1 October 2021. Even with a last-minute move from in-person to virtual, an …
A multiplex liquid chromatography tandem mass spectrometry method for the quantification of seven therapeutic monoclonal antibodies: application for adalimumab …
T Willeman, JF Jourdil, E Gautier-Veyret, B Bonaz… - Analytica chimica …, 2019 - Elsevier
The use of therapeutic monoclonal antibodies (mAbs) is steadily increasing. Previous
studies have reported the clinical interest of mAb therapeutic-drug monitoring (TDM) …
studies have reported the clinical interest of mAb therapeutic-drug monitoring (TDM) …
Personalized medicine of monoclonal antibodies in inflammatory bowel disease: pharmacogenetics, therapeutic drug monitoring, and beyond
A Di Paolo, G Luci - Frontiers in Pharmacology, 2021 - frontiersin.org
The pharmacotherapy of inflammatory bowel diseases (Crohn's disease and ulcerative
colitis) has experienced significant progress with the advent of monoclonal antibodies …
colitis) has experienced significant progress with the advent of monoclonal antibodies …
Voltammetric studies and spectroscopic investigations of the interaction of an anticancer drug bevacizumab-DNA and analytical applications of disposable pencil …
A sensitive, simple, fast electrochemical biosensor for the DNA interaction of bevacizumab
(BEVA), which is used as a targeted drug in cancer treatment, was developed using the …
(BEVA), which is used as a targeted drug in cancer treatment, was developed using the …
Cross-validation of a multiplex LC-MS/MS method for assaying mAbs plasma levels in patients with cancer: a GPCO-UNICANCER study
C Marin, N Khoudour, A Millet, D Lebert, P Bros… - Pharmaceuticals, 2021 - mdpi.com
Background: Different liquid chromatography tandem mass spectrometry (LC–MS/MS)
methods have been published for quantification of monoclonal antibodies (mAbs) in plasma …
methods have been published for quantification of monoclonal antibodies (mAbs) in plasma …
Quantification of nivolumab in human plasma by LC-MS/HRMS and LC-MS/MS, comparison with ELISA
A Millet, N Khoudour, P Bros, D Lebert, G Picard… - Talanta, 2021 - Elsevier
Nivolumab is a fully human immunoglobulin G4 used for the treatment of several advanced
solid cancers as immune checkpoint inhibitors. There are some challenges for the …
solid cancers as immune checkpoint inhibitors. There are some challenges for the …
Determination of plasma concentration of Belimumab by LC-MS/MS: method development, validation, and clinical application
C Marin, G Noé, D Schlemmer, Q Beaulieu… - … of Pharmaceutical and …, 2023 - Elsevier
Introduction Belimumab is a monoclonal antibody against B cell activating factor (BLyS).
This monoclonal antibody (mAb) has been shown to be effective in reducing disease activity …
This monoclonal antibody (mAb) has been shown to be effective in reducing disease activity …
Bottom-up sample preparation for the LC–MS/MS quantification of anti-cancer monoclonal antibodies in bio matrices
KAM de Jong, SJ van Breugel, MJX Hillebrand… - Bioanalysis, 2020 - Taylor & Francis
Therapeutic monoclonal antibodies (mAbs) are rapidly taking over the treatment of many
malignancies, and an astonishing number of mAbs is in development. This causes a high …
malignancies, and an astonishing number of mAbs is in development. This causes a high …