Nanoscience has matured significantly during the last decade as it has transitioned from
bench top science to applied technology. Presently, nanomaterials are used in a wide …

Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs).
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …

Ambient particulate matter (PM) is an environmental factor that has been associated with
increased respiratory morbidity and mortality. The major effect of ambient PM on the …

Nanotoxicology is emerging as an important subdiscipline of nanotechnology.
Nanotoxicology refers to the study of the interactions of nanostructures with biological …

Virus-like particles (VLPs) are formed by the self-assembly of envelope and/or capsid
proteins from many viruses. In many cases such VLPs have structural characteristics and …

Development of safe and effective cancer vaccine formulation is a primary focus in the field
of cancer immunotherapy. The recognition of the crucial role of dendritic cells (DCs) in …

Purpose: The initial goal of this study was to test the immunologic and clinical effects of a
new cancer vaccine consisting of dendritic cells (DC) transduced with the full-length wild …

Influenza is a zoonotic viral disease that represents a health and economic threat to both
humans and animals worldwide. Swine influenza (SI) was first recognized clinically in pigs …

Abstract Poly (lactide-co-glycolide)(PLGA) particles have strong potential as antigen delivery
systems. The size of PLGA particles used to vaccinate mice can affect the magnitude of the …

Polymeric nano-and microparticles have recently been shown to possess significant
potential as drug delivery systems. In particular, the use of biodegradable polymeric …