Importance Chronic critical limb ischemia, marked by intractable lower extremity ischemic
rest pain and tissue loss, is a highly morbid condition that leads to the loss of ambulation …

Níveis de evidência Nível A Dados obtidos a partir de múltiplos estudos randomizados de
bom porte, concordantes e/ou de meta-análise robusta de estudos clínicos randomizados …

Background: Acute aortic syndromes (AASs) are rare and severe cardiovascular
emergencies with unspecific symptoms. For AASs, both misdiagnosis and overtesting are …

Level of evidence Level A Data obtained from multiple concordant large randomized trials
and/or robust meta-analysis of randomized clinical trials Level B Data obtained from less …

Objectives To determine the accuracy of coding of admissions for stroke on weekdays
versus weekends and any impact on apparent outcome. Design Prospective population …

Acute Limb Ischemia (ALI) of the lower limb is defined as a sudden drop in arterial limb
perfusion, which is a medical emergency requiring prompt intervention with high amputation …

The role of CD4+ T cells in the ischemic tissues of T2D patients remains unclear. Here, we
report that T2D patients' vascular density was negatively correlated with the number of …

Middle-aged adults can start to be affected by some arterial diseases (ADs), such as
abdominal aortic or popliteal artery aneurysms, lower extremity arterial disease, internal …

Objective: We aimed to estimate the effect of blood pressure (BP) traits and BP-lowering
medications (via genetic proxies) on peripheral artery disease. Approach and Results …

Acute limb ischemia (ALI) is a vascular emergency associated with a high risk for limb loss
and death. Most cases result from in situ thrombosis in patients with preexisting peripheral …