Simultaneous recording of cytosolic and sarco-endoplasmic reticulum (SR/ER) luminal free
calcium concentrations ([Ca2+] i and [Ca2+] L, respectively) supports the notion that release …

Ryanodine receptors are Ca 2+ release channels of internal stores. This review focuses on
those situations and conditions that transform RyRs from a finely regulated ion channel to an …

Wnt signaling has a crucial role in synaptic function at the central nervous system. Here we
evaluate whether Wnts affect nitric oxide (NO) generation in hippocampal neurons. We …

OBJECTIVE To study the involvement of extracellular Ca2+ and the properties of the
intracellular Ca2+ ([Ca2+] i) stores on the carbachol‐induced contraction of mammalian …

PKC inhibitors stimulate Ca2+ release from internal stores in diverse cell types. Our data
indicate that this action cannot be explained by an increased agonist-induced IP3 …

Although lysophosphatidic acid (LPA) is known to increase intracellularfree calcium
concentration ([Ca2+] i) in different cell types, the effect of LPA on the skeletal muscle cells is …

The sarcoplasmic/endoplasmic reticulum (SR/ER) is the main intracellular calcium (Ca 2+)
pool in muscle and non-muscle eukaryotic cells, respectively. The reticulum accumulates Ca …

We have previously shown that rapid inhibition of sarcoplasmic reticulum (SR) ATPase
(SERCA pumps) decreases the amplitude and rate of rise (synchronization) of caffeine …

Sarcoplasmic reticulum contains the internal Ca2+ store in smooth muscle cells and its
lumen appears to be a continuum that lacks diffusion barriers. Accordingly, the free luminal …

Publisher Summary A variety of calcium signals can be produced by smooth muscle.
Calcium signals in smooth muscles are associated with contraction and relaxation and the …