Circular RNAs in pulmonary hypertension: emerging biological concepts and potential mechanism
Q Wang, Y Sun, Q Zhao, W Wu, L Wang… - Animal Models and …, 2022 - Wiley Online Library
Circular RNAs (circRNAs) are endogenous RNAs with a covalently closed single‐stranded
transcript. They are a novel class of genomic regulators that are linked to many important …
transcript. They are a novel class of genomic regulators that are linked to many important …
The role of glutamine and glutaminase in pulmonary hypertension
S Wang, Y Yan, WJ Xu, SG Gong, XJ Zhong… - Frontiers in …, 2022 - frontiersin.org
Pulmonary hypertension (PH) refers to a clinical and pathophysiological syndrome in which
pulmonary vascular resistance and pulmonary arterial pressure are increased due to …
pulmonary vascular resistance and pulmonary arterial pressure are increased due to …
Plasma metabolomics in the perioperative period of defect repair in patients with pulmonary arterial hypertension associated with congenital heart disease
The quality of life and survival rates of patients with pulmonary arterial hypertension
associated with congenital heart disease (CHD–PAH) have been greatly improved by defect …
associated with congenital heart disease (CHD–PAH) have been greatly improved by defect …
Integrated metabolomics and mechanism to reveal the protective effect of kaempferol on pulmonary arterial hypertension
J Yi, X Wang, K Song, J Ren, H Che, H Yu… - Journal of Pharmaceutical …, 2022 - Elsevier
Currently, there have been breakthroughs in the study of the underlying mechanisms of
pulmonary arterial hypertension, but treatment is still challenging. The aim of this study was …
pulmonary arterial hypertension, but treatment is still challenging. The aim of this study was …
Metabolomics meets clinics: a multivariate analysis of plasma and urine metabolic signatures in pulmonary arterial hypertension
R Wawrzyniak, P Grešner, E Lewicka… - Journal of Proteome …, 2023 - ACS Publications
Pulmonary arterial hypertension (PAH) is a severe, multifactorial, and frequently
misdiagnosed disorder. The aim of this observational study was to compare the plasma and …
misdiagnosed disorder. The aim of this observational study was to compare the plasma and …
Implication of proliferation gene biomarkers in pulmonary hypertension
Abstract Objective/Background Proliferation is a widely recognized trigger for pulmonary
hypertension (PH), a life‐threatening, progressive disorder of pulmonary blood vessels. This …
hypertension (PH), a life‐threatening, progressive disorder of pulmonary blood vessels. This …
Right ventricle remodeling metabolic signature in experimental pulmonary hypertension models of chronic hypoxia and monocrotaline exposure
T Hautbergue, F Antigny, A Boët, F Haddad, B Masson… - Cells, 2021 - mdpi.com
Introduction: Over time and despite optimal medical management of patients with pulmonary
hypertension (PH), the right ventricle (RV) function deteriorates from an adaptive to …
hypertension (PH), the right ventricle (RV) function deteriorates from an adaptive to …
Interstage single ventricle heart disease infants show dysregulation in multiple metabolic pathways: targeted metabolomics analysis
BS Frank, L Khailova, J Dekermanjian, MB Mitchell… - JACC: Advances, 2023 - jacc.org
Background Infants with SVHD experience morbidity related to pulmonary vascular
inadequacy. Metabolomic analysis involves a systems biology approach to identifying novel …
inadequacy. Metabolomic analysis involves a systems biology approach to identifying novel …
Animal models of pulmonary hypertension due to left heart disease
Pulmonary hypertension due to left heart disease (PH‐LHD) is regarded as the most
prevalent form of pulmonary hypertension (PH). Indeed, PH is an independent risk factor …
prevalent form of pulmonary hypertension (PH). Indeed, PH is an independent risk factor …
Metabolic reprogramming: A novel metabolic model for pulmonary hypertension
X Liu, L Zhang, W Zhang - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Pulmonary arterial hypertension, or PAH, is a condition that is characterized by pulmonary
artery pressures above 20 mmHg (at rest). In the treatment of PAH, the pulmonary vascular …
artery pressures above 20 mmHg (at rest). In the treatment of PAH, the pulmonary vascular …