Cell plasticity represents the ability of cells to be reprogrammed and to change their fate and
identity, enabling homeostasis restoration and tissue regeneration following damage. Cell …

The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …

Epithelial-mesenchymal transition (EMT) is a transient, reversible process of cell de-
differentiation where cancer cells transit between various stages of an EMT continuum …

Epithelial-to-mesenchymal transition (EMT) regulates tumour initiation, progression,
metastasis and resistance to anti-cancer therapy,,,,,–. Although great progress has been …

Profiling tumors at single-cell resolution provides an opportunity to understand complexities
underpinning lymph-node metastases in head and neck squamous-cell carcinoma. Single …

Metastasis remains the leading cause of cancer-associated mortality, and a detailed
understanding of the metastatic process could suggest new therapeutic avenues. However …

Within a tumor, cancer cells exist in different states that are associated with distinct tumor
functions, including proliferation, differentiation, invasion, metastasis, and resistance to anti …

The tumor microenvironment (TME) corresponds to a complex and dynamic interconnection
between the extracellular matrix and malignant cells and their surrounding stroma …

Metastasis is a multistep process by which cancer cells break away from their original
location and spread to distant organs, and is responsible for the vast majority of cancer …

Epithelial-to-mesenchymal transition (EMT), a biological phenomenon of cellular plasticity
initially reported in embryonic development, has been increasingly recognized for its …