Hepatic encephalopathy: Novel insights into classification, pathophysiology and therapy

CF Rose, P Amodio, JS Bajaj, RK Dhiman… - Journal of …, 2020 - Elsevier
Hepatic encephalopathy (HE) is a frequent and serious complication of both chronic liver
disease and acute liver failure. HE manifests as a wide spectrum of neuropsychiatric …

The gut–liver axis and the intersection with the microbiome

A Tripathi, J Debelius, DA Brenner, M Karin… - Nature reviews …, 2018 - nature.com
In the past decade, an exciting realization has been that diverse liver diseases—ranging
from nonalcoholic steatohepatitis, alcoholic steatohepatitis and cirrhosis to hepatocellular …

Sugar alcohols—their role in the modern world of sweeteners: a review

M Grembecka - European Food Research and Technology, 2015 - Springer
Epidemic obesity and diabetes encouraged the changes in population lifestyle and
consumers' food products awareness. Food industry has responded people's demand by …

Management of the critically ill patient with cirrhosis: a multidisciplinary perspective

MK Nadim, F Durand, JA Kellum, J Levitsky… - Journal of …, 2016 - Elsevier
Methods Prior to the conference, the organizing committee identified topics relevant to the
management of patients with ACLF. A diverse international panel representing multiple …

Rifaximin treatment in hepatic encephalopathy

NM Bass, KD Mullen, A Sanyal… - … England Journal of …, 2010 - Mass Medical Soc
Background Hepatic encephalopathy is a chronically debilitating complication of hepatic
cirrhosis. The efficacy of rifaximin, a minimally absorbed antibiotic, is well documented in the …

A randomized, double-blind, controlled trial comparing rifaximin plus lactulose with lactulose alone in treatment of overt hepatic encephalopathy

BC Sharma, P Sharma, MK Lunia… - Official journal of the …, 2013 - journals.lww.com
OBJECTIVES: Hepatic encephalopathy (HE) is associated with poor prognosis in cirrhosis.
Drugs used in the treatment of HE are primarily directed at the reduction of the blood …

Covert and overt hepatic encephalopathy: diagnosis and management

KR Patidar, JS Bajaj - Clinical Gastroenterology and Hepatology, 2015 - Elsevier
Hepatic encephalopathy (HE) is part of a spectrum of neurocognitive changes in cirrhosis.
HE is divided into 2 broad categories based on severity: covert hepatic encephalopathy …

[PDF][PDF] Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis

A Kumar, G Davuluri, RN Silva, MPKJ Engelen… - …, 2017 - Wiley Online Library
Sarcopenia or skeletal muscle loss is a frequent, potentially reversible complication in
cirrhosis that adversely affects clinical outcomes. Hyperammonemia is a consistent …

[HTML][HTML] Gut-liver axis in liver cirrhosis: How to manage leaky gut and endotoxemia

H Fukui - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
A “leaky gut” may be the cutting edge for the passage of toxins, antigens or bacteria into the
body, and may play a pathogenic role in advanced liver cirrhosis and its complications …

Non‐absorbable disaccharides versus placebo/no intervention and lactulose versus lactitol for the prevention and treatment of hepatic encephalopathy in people with …

LL Gluud, H Vilstrup… - Cochrane Database of …, 2016 - cochranelibrary.com
Background Non‐absorbable disaccharides (lactulose and lactitol) are recommended as
first‐line treatment for hepatic encephalopathy. The previous (second) version of this review …