[HTML][HTML] The therapeutic potential of second and third generation CB1R antagonists

R Cinar, MR Iyer, G Kunos - Pharmacology & therapeutics, 2020 - Elsevier
Endocannabinoids acting via CB 1 receptors (CB 1 R) play a critical role in regulating
energy homeostasis, which was the rationale for the pharmaceutical development of CB 1 R …

[HTML][HTML] Hepatic antifibrotic pharmacotherapy: are we approaching success?

Y Chang, H Li - Journal of clinical and translational hepatology, 2020 - ncbi.nlm.nih.gov
The incidence rate and mortality of liver fibrosis caused by various etiologies are high
throughout the world. Liver fibrosis, the subsequent cirrhosis and other serious related …

Intake, nutrient digestibility, rumen parameters, growth rate, carcase characteristics and cannabinoid residues of sheep fed pelleted rations containing hemp …

GL Krebs, DW De Rosa, DM White… - Translational Animal …, 2021 - academic.oup.com
The feeding value and impact of hemp stubble in the diet of ruminants is unknown. Fifteen
Merino castrated male sheep were maintained in individual pens and fed one of three …

The role of Nrf2 signaling in parasitic diseases and its therapeutic potential

M Vatankhah, R Panahizadeh, A Safari, A Ziyabakhsh… - Heliyon, 2024 - cell.com
In response to invading parasites, one of the principal arms of innate immunity is oxidative
stress, caused by reactive oxygen species (ROS). However, oxidative stresses play dual …

Reversine and herbal Xiang–Sha–Liu–Jun–Zi decoction ameliorate thioacetamide-induced hepatic injury by regulating the RelA/NF-κB/caspase signaling pathway

ZH Mai, Y Huang, D Huang, ZS Huang, ZX He… - Open Life …, 2020 - degruyter.com
This study investigated the anti-fibrotic effects of reversine and Chinese medicine Xiang–
Sha–Liu–Jun–Zi decoction (XSLJZD) on thioacetamide (TAA)-induced hepatic injury …

El sistema endocannabinoide en enfermedades digestivas

C Torres Pérez - dspace.umh.es
El Cannabis sativa L. es una planta históricamente utilizada con fines terapéuticos que ha
sido ilegalizada en muchos países por el riesgo de uso recreacional abusivo. Las …