Non-alcoholic fatty liver disease (NAFLD) has emerged pandemically across the globe and
particularly affects patients with obesity and type 2 diabetes. NAFLD is a complex systemic …

Today, persistent and uncontrolled inflammation is appreciated to play a pivotal role in many
diseases, such as cardiovascular diseases, neurodegenerative diseases, metabolic …

There have been many chapters written about macrophage polarization. These chapters
generally focus on the role of macrophages in orchestrating immune responses by …

Atherosclerosis is a lipid-driven inflammatory disease of the arterial intima in which the
balance of pro-inflammatory and inflammation-resolving mechanisms dictates the final …

Resolution is an active and highly coordinated process that occurs in response to
inflammation to limit tissue damage and promote repair. When the resolution program fails …

With cardiovascular disease being the leading cause of morbidity and mortality worldwide,
effective and cost-efficient therapies to reduce cardiovascular risk are highly needed. Lipids …

Omega-3 polyunsaturated fatty acids (PUFAs), including eicosapentaenoic acid,
docosapentaenoic acid and docosahexaenoic acid, display a wide range of beneficial …

A non-resolving inflammation results in a chronic inflammatory response, characteristic of
atherosclerosis, abdominal aortic aneurysms and several other cardiovascular diseases …

The rapid increase in both the lifespan and proportion of older adults is accompanied by the
unprecedented rise in age-associated chronic diseases, including sarcopenia and obesity …

A growing body of evidence suggests that the interaction between immune and metabolic
responses is essential for maintaining tissue and organ homeostasis. These interacting …