Membranous nephropathy: new pathogenic mechanisms and their clinical implications

E Hoxha, L Reinhard, RAK Stahl - Nature Reviews Nephrology, 2022 - nature.com
Membranous nephropathy (MN) is characterized histomorphologically by the presence of
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …

Membranous nephropathy: mechanistic insights and therapeutic perspectives

MR Hua, YL Zhao, JZ Yang, L Zou, YY Zhao… - International …, 2023 - Elsevier
Membranous nephropathy (MN) is one of the most common causes of non-diabetic
nephrotic syndrome in adults. About 80% of cases are renal limited (primary MN) and 20 …

Cytokines network in primary membranous nephropathy

Q Zhao, H Dai, Y Hu, H Jiang, Z Feng, W Liu… - International …, 2022 - Elsevier
There have been extensive studies on the immunological mechanism of primary
membranous nephropathy (PMN). Autoantibodies, being the end product of humoral auto …

[HTML][HTML] New-onset and relapsed membranous nephropathy post SARS-CoV-2 and COVID-19 vaccination

Q Ma, X Li, G Xu - Viruses, 2022 - mdpi.com
Since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak and
COVID-19 vaccination, new-onset and relapsed clinical cases of membranous nephropathy …

[HTML][HTML] Canagliflozin reverses Th1/Th2 imbalance and promotes podocyte autophagy in rats with membranous nephropathy

X Lv, J Wang, L Zhang, X Shao, Y Lin, H Liu… - Frontiers in …, 2022 - frontiersin.org
Idiopathic membranous nephropathy is the main cause of chronic kidney disease (CKD).
Studies have shown sodium–glucose co-transporter 2 (SGLT2) inhibitors significantly delay …

[HTML][HTML] Specific alterations of gut microbiota in patients with membranous nephropathy: A systematic review and meta-analysis

Y Zhang, J Zhao, Y Qin, Y Wang, Z Yu, X Ning… - Frontiers in …, 2022 - frontiersin.org
Background: The pathogenesis of idiopathic membranous nephropathy (IMN) has not yet
been thoroughly clarified, and gut dysbiosis may be a contributor to IMN. However, the …

[HTML][HTML] Serum 25-hydroxyvitamin D as a predictive biomarker of clinical outcomes in patients with primary membranous nephropathy

S Duan, S Chen, F Lu, M Zhou, L Jiang, C Chen… - Frontiers in …, 2023 - frontiersin.org
Background: Primary membranous nephropathy (PMN) is an immune-related disease with
increased morbidity and the most common cause of adult nephrotic syndrome (NS). The …

[HTML][HTML] Toxic occupational exposures and membranous nephropathy

M Cremoni, S Agbekodo, M Teisseyre… - Clinical Journal of the …, 2022 - journals.lww.com
Results Patients with membranous nephropathy worked more frequently in the construction
sector than the general population (33% versus 7%, P< 0.001). This difference remained …

[HTML][HTML] Single-cell RNA sequencing shows the immune cell landscape in the kidneys of patients with idiopathic membranous nephropathy

M Shi, Y Wang, H Zhang, Z Ling, X Chen… - Frontiers in …, 2023 - frontiersin.org
Idiopathic membranous nephropathy (IMN) is a leading pathological type of the adult
primary nephrotic syndrome. Some patients develop end-stage renal disease due to poor …

[HTML][HTML] Role of histone deacetylases in T-cell development and function

M Pieniawska, K Iżykowska - International Journal of Molecular Sciences, 2022 - mdpi.com
Histone deacetylases (HDACs) are a group of enzymes called “epigenetic erasers”. They
remove the acetyl group from histones changing the condensation state of chromatin …