During the last decade, the spectre of an influenza pandemic of avian origin has led to a
revision of national and global pandemic preparedness plans and has stressed the need for …

In recent years, the use of plants as bioreactors has emerged as an exciting area of research
and significant advances have created new opportunities. The driving forces behind the …

In the molecular farming area, transient expression approaches for pharmaceutical proteins
production, mainly recombinant monoclonal antibodies and vaccines, were developed …

Plants have been identified as promising expression systems for commercial production of
vaccine antigens. In phase I clinical trials several plant-derived vaccine antigens have been …

The 21st century saw a great expansion in the bioprocess and biopharmaceutical sectors.
Rising demand gave rise to newer technology for better yield and performance. The …

Background During a global influenza pandemic, the vaccine requirements of developing
countries can surpass their supply capabilities, if these exist at all, compelling them to rely …

A synthetic hemagglutinin (HA) gene from the highly pathogenic avian influenza (HPAI) virus
A/chicken/Indonesia/7/2003 (H5N1)(Indo/03) was expressed in aquatic plant Lemna minor …

We describe the expression and immunogenicity of a recombinant chimeric protein (HAV
VP1-Fc) consisting of human hepatitis A virus VP1 and an Fc antibody fragment using a …

Elastin-like peptide (ELP) was fused to two different avian flu H5N1 antigens and expressed
in transgenic tobacco plants. The presence of the ELP tag enhanced the accumulation of the …

Nanobodies®(VHH s) provide powerful tools in therapeutic and biotechnological
applications. Nevertheless, for some applications, bivalent antibodies perform much better …