Community-acquired bacterial meningitis

D van de Beek, M Brouwer, R Hasbun… - Nature reviews Disease …, 2016 - nature.com
Meningitis is an inflammation of the meninges and subarachnoid space that can also involve
the brain cortex and parenchyma. It can be acquired spontaneously in the community …

Incidence and aetiology of bacterial meningitis among children aged 1–59 months in South Asia: systematic review and meta-analysis

M Ali, BA Chang, KW Johnson, SK Morris - Vaccine, 2018 - Elsevier
Background Bacterial meningitis is a significant cause of morbidity and mortality worldwide
among children aged 1–59 months. We aimed to describe its burden in South Asia, focusing …

Density of Upper Respiratory Colonization With Streptococcus pneumoniae and Its Role in the Diagnosis of Pneumococcal Pneumonia Among Children Aged <5 …

HC Baggett, NL Watson, M Deloria Knoll… - Clinical Infectious …, 2017 - academic.oup.com
Background Previous studies suggested an association between upper airway
pneumococcal colonization density and pneumococcal pneumonia, but data in children are …

Sequential triplex real-time PCR assay for detecting 21 pneumococcal capsular serotypes that account for a high global disease burden

FC Pimenta, A Roundtree, A Soysal… - Journal of clinical …, 2013 - Am Soc Microbiol
We developed and validated a real-time PCR assay consisting of 7 triplexed reactions to
identify 11 individual serotypes plus 10 small serogroups representing the majority of …

A Streptococcus pneumoniae Type 2 Oligosaccharide Glycoconjugate Elicits Opsonic Antibodies and Is Protective in an Animal Model of Invasive Pneumococcal …

M Emmadi, N Khan, L Lykke, K Reppe… - Journal of the …, 2017 - ACS Publications
Invasive pneumococcal diseases (IPDs) remain the leading cause of vaccine-preventable
childhood death, even though highly effective pneumococcal conjugate vaccines (PCVs) are …

Disparities by sex in care-seeking behaviors and treatment outcomes for pneumonia among children admitted to hospitals in Bangladesh

A Naheed, RF Breiman, MS Islam, SK Saha… - PloS one, 2019 - journals.plos.org
Background Incidence of community acquired pneumonia is high globally. In Bangladesh,
more male children than female children are brought to hospitals for pneumonia. We …

Using pneumococcal and rotavirus surveillance in vaccine decision-making: a series of case studies in Bangladesh, Armenia and the Gambia

AZ Hasan, S Saha, SK Saha, G Sahakyan, S Grigoryan… - Vaccine, 2018 - Elsevier
Pneumonia and diarrhea are the leading causes of child morbidity and mortality globally
and are vaccine preventable. The WHO-coordinated Global Rotavirus and Invasive Bacterial …

Streptococcus pneumoniae genomic datasets from an Indian population describing pre-vaccine evolutionary epidemiology using a whole genome sequencing …

G Nagaraj, V Govindan, F Ganaie… - Microbial …, 2021 - microbiologyresearch.org
Globally, India has a high burden of pneumococcal disease, and pneumococcal conjugate
vaccine (PCV) has been rolled out in different phases across the country since May 2017 in …

Safety and immunogenicity of neonatal pneumococcal conjugate vaccination in Papua New Guinean children: a randomised controlled trial

WS Pomat, AHJ van den Biggelaar… - PLoS …, 2013 - journals.plos.org
Background Approximately 826,000 children, mostly young infants, die annually from
invasive pneumococcal disease. A 6-10-14-week schedule of pneumococcal conjugate …

In Silico Subtractive Proteomics and Molecular Docking Approaches for the Identification of Novel Inhibitors against Streptococcus pneumoniae Strain D39

A Shami, NK Alharbi, FA Al-Saeed, AA Alsaegh… - Life, 2023 - mdpi.com
Streptococcus pneumoniae is a notorious Gram-positive pathogen present asymptomatically
in the nasophayrnx of humans. According to the World Health Organization (WHO) …