Pediatric clinical trials

SB Bavdekar - Perspectives in clinical research, 2013 - journals.lww.com
It is worth remembering that with other vulnerable sections of the society, children bore the
brunt of ill‑effects of human experimentation. Use of thalidomide by pregnant women …

Mindfulness-based intervention development for children and adolescents

D Saunders, H Kober - Mindfulness, 2020 - Springer
Mindfulness-based interventions (MBIs) have become an increasingly widespread treatment
for psychiatric and medical disorders in children and adolescents. However, enthusiasm for …

Therapeutic guidelines for prescribing antibiotics in neonates should be evidence-based: a French national survey

S Leroux, W Zhao, P Bétrémieux, P Pladys… - Archives of disease in …, 2015 - adc.bmj.com
Objective This survey aims to describe and analyse the dosage regimens of antibiotics in
French neonatal intensive care units (NICUs). Methods Senior doctors from 56 French …

Communication about children's clinical trials as observed and experienced: qualitative study of parents and practitioners

V Shilling, PR Williamson, H Hickey, E Sowden… - PloS one, 2011 - journals.plos.org
Background Recruiting children to clinical trials is perceived to be challenging. To identify
ways to optimise recruitment and its conduct, we compared how parents and practitioners …

Inviting parents to take part in paediatric palliative care research: a mixed-methods examination of selection bias

JC Crocker, E Beecham, P Kelly… - Palliative …, 2015 - journals.sagepub.com
Background: Recruitment to paediatric palliative care research is challenging, with high
rates of non-invitation of eligible families by clinicians. The impact on sample characteristics …

Engaging fathers in pediatric palliative care research

D Nicholas, L Beaune, M Belletrutti… - … work in end-of-life & …, 2020 - Taylor & Francis
Fathers are under-represented in pediatric palliative care research despite frequently
playing a key role in the lives of their children. The purpose of this study was to identify …

Appealing to altruism is not enough: motivators for participating in health services research

J Hunter, K Corcoran, S Leeder… - Journal of Empirical …, 2012 - journals.sagepub.com
This pilot study sought to identify motivators and barriers to participating in a longitudinal
survey; we interviewed patients and practitioners at a multidisciplinary primary care clinic …

Recruitment in pediatric clinical research was influenced by study characteristics and pediatricians' perceptions: a multicenter survey

F Kaguelidou, P Amiel, A Blachier, C Iliescu… - Journal of clinical …, 2013 - Elsevier
Objectives The aim of this survey was to quantify refusal rates and identify factors of refusal
pertaining to studies and recruiting pediatricians in the research recruitment process. Study …

Randomized controlled trials of antibiotics for neonatal infections: a systematic review

F Kaguelidou, MA Turner, I Choonara… - British Journal of …, 2013 - Wiley Online Library
Aims Antibiotics are a key resource for the management of infectious diseases in
neonatology and their evaluation is particularly challenging. We reviewed medical literature …

Parental consent to participation in a randomised trial in children: associated child, family, and physician factors

P Sureshkumar, P Caldwell, A Lowe… - Clinical …, 2012 - journals.sagepub.com
Background Low participation rates in randomised controlled trials involving children are
almost a universal problem, leading to high cost and low statistical power. Trial …