Despite the advent of new diagnostics, drugs and regimens, tuberculosis (TB) remains a
global public health threat. A significant challenge for TB control efforts has been the …

Abstract Purpose of Review Additional imaging modalities, such as FDG-PET/CT, have been
included into the workup for patients with suspected infective endocarditis, according to …

BACKGROUND Matrix metalloproteinases (MMPs) are key regulators of tissue destruction in
tuberculosis (TB) and may be targets for host-directed therapy. We conducted a phase II …

While not conventionally used as the first-line modality,[18 F]-2-fluoro-2-deoxy-D-glucose
(FDG)-positron emission tomography/computed tomography (PET/CT) can identify infection …

The innate immune system plays a key role as the first line of defense in various human
diseases including cancer, cardiovascular and inflammatory diseases. In contrast to tissue …

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), accounts for
over ten million infections and over 1.5 million deaths every year [1]. Upon infection, the …

Positron emission tomography–computed tomography (PET-CT) has the potential to
revolutionize research in infectious diseases, as it has done with cancer. There is growing …

Nearly 140 years after Robert Koch discovered Mycobacterium tuberculosis, tuberculosis
(TB) remains a global threat and a deadly human pathogen. M. tuberculosis is notable for …

Background To predict tuberculosis (TB) treatment outcomes at an early stage, prevent poor
outcomes of drug-resistant tuberculosis (DR-TB) and interrupt transmission. Methods An …

Adjunctive rosuvastatin for rifampicin-susceptible pulmonary tuberculosis (rs-PTB) shows no
effect on microbiological or radiological outcomes in a phase IIb randomised, controlled trial …