SLC6 neurotransmitter transporters: structure, function, and regulation

AS Kristensen, J Andersen, TN Jørgensen… - Pharmacological …, 2011 - Elsevier
The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …

Plasma membrane monoamine transporters: structure, regulation and function

GE Torres, RR Gainetdinov, MG Caron - Nature Reviews Neuroscience, 2003 - nature.com
The classical biogenic amine neurotransmitters—dopamine, noradrenaline, and 5-
hydroxytryptamine—control a variety of functions including locomotion, autonomic function …

Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake

MM Bliziotes, AJ Eshleman, XW Zhang, KM Wiren - Bone, 2001 - Elsevier
Neurotransmitter regulation of bone metabolism has been the subject of increasing interest
and investigation. Because serotonin (5-HT) plays a role as a regulator of craniofacial …

5-hydroxytryptamine in the cardiovascular system: focus on the serotonin transporter (SERT).

W Ni, SW Watts - Clinical & Experimental Pharmacology & …, 2006 - search.ebscohost.com
The function of the serotonin transporter (SERT) is to take up and release serotonin (5-
hydroxytyptamine (5-HT)) from cells and this function of SERT in the central nervous system …

MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment

CD Verrico, GM Miller, BK Madras - Psychopharmacology, 2007 - Springer
Abstract Rationale 3, 4-Methylenedioxymethamphetamine (MDMA, designated as “Ecstasy”
if illicitly marketed in tablet form) induces significant decrements in neuronal serotonin (5 …

Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain

A Amphoux, V Vialou, E Drescher, M Brüss… - …, 2006 - Elsevier
Organic cation transporters (OCTs) are polyspecific carriers implicated in low-affinity,
corticosteroid-sensitive extraneuronal catecholamine uptake in peripheral tissues. The three …

Extreme enhancement or depletion of serotonin transporter function and serotonin availability in autism spectrum disorder

VR Garbarino, TL Gilman, LC Daws, GG Gould - Pharmacological research, 2019 - Elsevier
A variety of human and animal studies support the hypothesis that serotonin (5-
hydroxytryptamine or 5-HT) system dysfunction is a contributing factor to the development of …

Mutations in the Caenorhabditis elegans serotonin reuptake transporter MOD-5 reveal serotonin-dependent and-independent activities of fluoxetine

R Ranganathan, ER Sawin, C Trent… - Journal of …, 2001 - Soc Neuroscience
We isolated two mutants defective in the uptake of exogenous serotonin (5-HT) into the
neurosecretory motor neurons of Caenorhabditis elegans. These mutants were …

Ontogeny and regulation of the serotonin transporter: providing insights into human disorders

LC Daws, GG Gould - Pharmacology & therapeutics, 2011 - Elsevier
Abstract Serotonin (5-hydroxytryptamine, 5-HT) was one of the first neurotransmitters for
which a role in development was identified. Pharmacological and gene knockout studies …

Voltammetric characterization of the effect of monoamine uptake inhibitors and releasers on dopamine and serotonin uptake in mouse caudate-putamen and …

CE John, SR Jones - Neuropharmacology, 2007 - Elsevier
Fast scan cyclic voltammetry is an electrochemical technique used to measure dynamics of
transporter-mediated monoamine uptake in real time and provides a tool to evaluate the …