Pro-oxidant actions of carotenoids in triggering apoptosis of cancer cells: A review of emerging evidence

J Shin, MH Song, JW Oh, YS Keum, RK Saini - Antioxidants, 2020 - mdpi.com
Carotenoids are well known for their potent antioxidant function in the cellular system.
However, in cancer cells with an innately high level of intracellular reactive oxygen species …

Medicinal plants used against hepatic disorders in Bangladesh: a comprehensive review

R Das, S Mitra, AM Tareq, TB Emran… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Liver disease is a major cause of illness and death
worldwide which accounts for approximately 2 million deaths per year worldwide, 1 million …

[HTML][HTML] Emerging nanoformulation strategies for phytocompounds and applications from drug delivery to phototherapy to imaging

HS Han, SY Koo, KY Choi - Bioactive Materials, 2022 - Elsevier
Over thousands of years, natural bioactive compounds derived from plants (bioactive
phytocompounds, BPCs) have been used worldwide to address human health issues …

Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back

L Koklesova, A Liskova, M Samec, C Buhrmann… - Cancers, 2020 - mdpi.com
An incidence and mortality of cancer are rapidly growing worldwide, especially due to
heterogeneous character of the disease that is associated with irreversible impairment of …

Carotenoids and apocarotenoids in planta: Their role in plant development, contribution to the flavour and aroma of fruits and flowers, and their nutraceutical benefits

AJ Simkin - Plants, 2021 - mdpi.com
Carotenoids and apocarotenoids are diverse classes of compounds found in nature and are
important natural pigments, nutraceuticals and flavour/aroma molecules. Improving the …

Modulation of dysregulated cancer metabolism by plant secondary metabolites: A mechanistic review

S Fakhri, SZ Moradi, MH Farzaei, A Bishayee - Seminars in cancer biology, 2022 - Elsevier
Several signaling pathways and basic metabolites are responsible for the control of
metabolism in both normal and cancer cells. As emerging hallmarks of cancer metabolism …

The role of bixin as antioxidant, anti-inflammatory, anticancer, and skin protecting natural product extracted from Bixa orellana L

A Ashraf, MU Ijaz, S Muzammil, MM Nazir, S Zafar… - Fitoterapia, 2023 - Elsevier
Since long, medicinal plants or herbs are being used in different traditional treatment
systems as therapeutic agents to treat a variety of illnesses. Bixa orellana L., an medicinal …

Phytochemicals from Indian ethnomedicines: Promising prospects for the management of oxidative stress and cancer

N Fatima, SSR Baqri, A Alsulimani, S Fagoonee… - Antioxidants, 2021 - mdpi.com
Oxygen is indispensable for most organisms on the earth because of its role in respiration.
However, it is also associated with several unwanted effects which may sometimes prove …

Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway

Y Zhu, D Sun, H Liu, L Sun, J Jie, J Luo, L Peng… - International …, 2021 - Elsevier
Accumulating evidence has implicated the potential of natural compounds in treatment of
asthma. Bixin is a natural food coloring isolated from the seeds of Bixa Orellana, which …

Bixin attenuates carbon tetrachloride induced oxidative stress, inflammation and fibrosis in kidney by regulating the Nrf2/TLR4/MyD88 and PPAR-γ/TGF-β1/Smad3 …

JQ Ma, YJ Zhang, ZK Tian, CM Liu - International immunopharmacology, 2021 - Elsevier
Bixin, an natural carotenoid extracted from the seeds of the Bixa orellana has been shown to
possess numerous important pharmacological activities. The present study was aimed to …