The 2020 WHO classification of tumors of bone: an updated review

JH Choi, JY Ro - Advances in anatomic pathology, 2021 - journals.lww.com
Bone tumors are a rare and heterogeneous group of neoplasms that occur in the bone. The
diversity and considerable morphologic overlap of bone tumors with other mesenchymal …

Cartilage tumours and bone development: molecular pathology and possible therapeutic targets

JVMG Bovée, PCW Hogendoorn, JS Wunder… - Nature Reviews …, 2010 - nature.com
As a group, cartilage tumours are the most common primary bone lesions. They range from
benign lesions, such as enchondromas and osteochondromas, to malignant …

Bone sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

PCW Hogendoorn, N Athanasou, S Bielack… - Annals of …, 2010 - annalsofoncology.org
background A general overview of the histological types of primary malignant bone tumour
according to the World Health Organization (WHO) classification is given in Table 1. Several …

Novel therapeutic approaches in chondrosarcoma

G Polychronidou, V Karavasilis, SM Pollack… - Future …, 2017 - Taylor & Francis
Chondrosarcoma is a malignant tumor of bones, characterized by the production of cartilage
matrix. Due to lack of effective treatment for advanced disease, the clinical management of …

Phase 2 study of dasatinib in patients with alveolar soft part sarcoma, chondrosarcoma, chordoma, epithelioid sarcoma, or solitary fibrous tumor

SM Schuetze, V Bolejack, E Choy, KN Ganjoo… - Cancer, 2017 - Wiley Online Library
BACKGROUND Alveolar soft part sarcoma (ASPS), chondrosarcoma (CS), chordoma,
epithelioid sarcoma, and solitary fibrous tumor (SFT) are malignant tumors that are relatively …

Advances in sarcoma diagnostics and treatment

AR Dancsok, K Asleh-Aburaya, TO Nielsen - Oncotarget, 2016 - pmc.ncbi.nlm.nih.gov
The heterogeneity of sarcomas with regard to molecular genesis, histology, clinical
characteristics, and response to treatment makes management of these rare yet diverse …

Survival and prognostic factors in chondrosarcoma: results in 115 patients with long-term follow-up

D Andreou, S Ruppin, S Fehlberg, D Pink… - Acta …, 2011 - Taylor & Francis
Background and purpose There have been few long-term studies on the outcome of
chondrosarcoma and the findings regarding prognostic factors are controversial. We …

Chondrosarcoma: An overview of clinical behavior, molecular mechanisms mediated drug resistance and potential therapeutic targets

E Nazeri, MG Savadkoohi, K Majidzadeh-A… - Critical reviews in …, 2018 - Elsevier
Sarcomas are known as a heterogeneous class of cancers arisen in the connective tissues
and demonstrated various histological subtypes including both soft tissue and bone origin …

SARC009: phase 2 study of dasatinib in patients with previously treated, high‐grade, advanced sarcoma

SM Schuetze, JK Wathen, DR Lucas, E Choy… - Cancer, 2016 - Wiley Online Library
BACKGROUND Dasatinib exhibited activity in preclinical models of sarcoma. The Sarcoma
Alliance for Research through Collaboration (SARC) conducted a multicenter, phase 2 trial …

Chondrosarcoma: a rare misfortune in aging human cartilage? The role of stem and progenitor cells in proliferation, malignant degeneration and therapeutic …

KA Boehme, SB Schleicher, F Traub… - International journal of …, 2018 - mdpi.com
Unlike other malignant bone tumors including osteosarcomas and Ewing sarcomas with a
peak incidence in adolescents and young adults, conventional and dedifferentiated …