Plant-derived natural products for drug discovery: current approaches and prospects

N Nasim, IS Sandeep, S Mohanty - The Nucleus, 2022 - Springer
Nature has abundant source of drugs that need to be identified/purified for use as essential
biologics, either individually or in combination in the modern medical field. These drugs are …

Phytosomal curcumin: A review of pharmacokinetic, experimental and clinical studies

H Mirzaei, A Shakeri, B Rashidi, A Jalili… - Biomedicine & …, 2017 - Elsevier
Curcumin, a hydrophobic polyphenol, is the principal constituent extracted from dried
rhizomes of Curcuma longa L.(turmeric). Curcumin is known as a strong anti-oxidant and …

Nano-formulations of drugs: recent developments, impact and challenges

J Jeevanandam, Y San Chan, MK Danquah - Biochimie, 2016 - Elsevier
Nano-formulations of medicinal drugs have attracted the interest of many researchers for
drug delivery applications. These nano-formulations enhance the properties of conventional …

Berberine-induced bioactive metabolites of the gut microbiota improve energy metabolism

Y Wang, JW Shou, XY Li, ZX Zhao, J Fu, CY He… - Metabolism, 2017 - Elsevier
Objective Berberine (BBR) clinically lowers blood lipid and glucose levels via multi-target
mechanisms. One of the possible mechanisms is related to its effect on the short chain fatty …

Chitosan-based advanced materials for docetaxel and paclitaxel delivery: Recent advances and future directions in cancer theranostics

M Ashrafizadeh, Z Ahmadi, N Mohamadi… - International journal of …, 2020 - Elsevier
Paclitaxel (PTX) and docetaxel (DTX) are key members of taxanes with high anti-tumor
activity against various cancer cells. These chemotherapeutic agents suffer from a number of …

Exploring the use of nanocarrier systems to deliver the magical molecule; curcumin and its derivatives

M Mehanny, RM Hathout, AS Geneidi… - Journal of controlled …, 2016 - Elsevier
Curcumin and its derivatives; curcuminoids have been proven as potential remedies in
different diseases. However, their delivery carries several challenges owing to their poor …

[HTML][HTML] Novel nanomicelle formulation to enhance bioavailability and stability of curcuminoids

M Hatamipour, A Sahebkar, SH Alavizadeh… - Iranian journal of …, 2019 - ncbi.nlm.nih.gov
Objective (s): Curcuminoids, comprising curcumin, demethoxycurcumin (DMC) and
bisdemethoxycurcumin (BDMC), are bioactive phytochemicals with numerous …

Delivery of dual drug loaded lipid based nanoparticles across the blood–brain barrier impart enhanced neuroprotection in a rotenone induced mouse model of …

P Kundu, M Das, K Tripathy… - ACS chemical …, 2016 - ACS Publications
Parkinson's disease (PD) is the most widespread form of dementia where there is an age
related degeneration of dopaminergic neurons in the substantia nigra region of the brain …

Pharmacokinetic and pharmacodynamic features of nanoemulsion following oral, intravenous, topical and nasal route

H Choudhury, B Gorain, B Chatterjee… - Current …, 2017 - benthamdirect.com
Background: Most of the active pharmaceutical ingredients discovered recently in
pharmaceutical field exhibits poor aqueous solubility that pose major problem in their oral …

Plant extracts: from encapsulation to application

B Armendáriz-Barragán, N Zafar, W Badri… - Expert Opinion on …, 2016 - Taylor & Francis
Introduction: Plants are a natural source of various products with diverse biological activities
offering treatment for several diseases. Plant extract is a complex mixture of compounds …