Antimicrobial resistance (AMR) has become a major problem in public health leading to an
estimated 4.95 million deaths in 2019. The selective pressure caused by the massive and …

Throughout scientific literature, we can find evidence that antimicrobial resistance has
become a big problem in the recent years on a global scale. Public healthcare systems all …

A novel type of coumarin thiazoles as unique multi-targeting antimicrobial agents were
developed through four steps including cyclization, nucleophilic substitution and …

New antibacterial 3-(aminothiazolyl) quinolones (ATQs) were designed and efficiently
synthesized to counteract the growing multidrug resistance in animal husbandry. Bioactive …

Unique benzopyridone cyanoacetates (BCs) as new type of promising broad-spectrum
antibacterial candidates were discovered with large potential to combat the lethal multidrug …

Antibiotic resistance (AR) is a silent pandemic that kills millions worldwide. Although the
development of new therapeutic agents against antibiotic resistance is in urgent demand …

A series of 2-aminothiazole sulfanilamide oximes were developed as new membrane active
antibacterial agents to conquer the microbial infection. Benzoyl derivative 10c was …

Biofilms are a common survival strategy employed by bacteria in healthcare settings, which
enhances their resistance to antimicrobial and biocidal agents making infections difficult to …

Antimicrobial resistance is a global problem, rendering conventional treatments less
effective and requiring innovative strategies to combat this growing threat. The tripartite …

A class of structurally unique para-aminobenzenesulfonyl oxadiazoles as new potential
antimicrobial agents was designed and synthesized from acetanilide. Some target para …