Striatal cholinergic interneurons (ChIs) are central for the processing and reinforcement of
reward‐related behaviors that are negatively affected in states of altered dopamine …

Although dopamine D1 and D2 receptors belong to distinct subfamilies of dopamine
receptors, several lines of evidence indicate that they are functionally linked. However, a …

There is strong evidence for the existence of Gq/11-coupled dopamine receptors in the brain
but the mechanism by which dopamine signaling activates Gq/11, or its roles in neuronal …

BACKGROUND: The dopamine precursor 3, 4-dihydroxyphenyl-l-alanine (L-DOPA) is
currently the most efficacious noninvasive therapy for Parkinson's disease. A major …

Cannabinoid CB 1 receptors are densely expressed on striatal projection neurons
expressing dopamine D 1 or D 2 receptors. However, the specific neuronal distribution of CB …

Dopamine is one of the principal neurotransmitters in the basal ganglia, where it plays a
critical role in motor control and cognitive function through its interactions with the specific …

In this report, we investigated whether the D5 dopamine receptor, given its structural and
sequence homology with the D1 receptor, could interact with the D2 receptor to mediate a …

Compulsive drug-seeking behavior and its renewal in former drug addicts is promoted by
several situations, among which reactivation of drug withdrawal memories plays a crucial …

Repeated exposure to psychomotor stimulants produces a striking behavioral syndrome
involving repetitive, stereotypic behaviors that occur if an additional exposure to the …

Activation of D1-like (D1, D5) or D2-like (D1, D3, D4) dopamine receptors in the nucleus
accumbens shell is sufficient to reinstate cocaine-seeking behavior in rats. The goal of these …