Epithelial cells are the most common cell type in all animals, forming the sheets and tubes
that compose most organs and tissues. Apical–basal polarity is essential for epithelial cell …

During vertebrate development, a wide variety of cell types and tissues emerge from a single
fertilized oocyte. One of these tissues, the central nervous system, contains many types of …

Long-term ex vivo live imaging combined with unbiased sampling of cycling precursors
shows that macaque outer subventricular zone (OSVZ) includes four distinct basal radial …

Radial glia cells function as neural stem cells in the developing brain and generate self-
renewing and differentiating daughter cells by asymmetric cell divisions. During these …

Vertebrates have a unique 3D body shape in which correct tissue and organ shape and
alignment are essential for function. For example, vision requires the lens to be centred in …

Neurogenesis in the developing central nervous system consists of the induction and
proliferation of neural progenitor cells and their subsequent differentiation into mature …

Highlights•Gyrification is wide-spread in all mammalian lineages.•The program for
gyrification can be elicited in mice with a lissencephalic cortex.•Amplification of several types …

The mechanisms governing the expansion of neuron number in specific brain regions are
still poorly understood. Enlarged neuron numbers in different species are often anticipated …

Neural stem and progenitor cells giving rise to neurons in developing mammalian neocortex
fall into two principal classes with regard to location of mitosis—apical and basal, and into …

The adult central nervous system (CNS) of the zebrafish, owing to its enrichment in
constitutive neurogenic niches, is becoming an increasingly used model to address …