Exosome: a review of its classification, isolation techniques, storage, diagnostic and targeted therapy applications

Y Zhang, J Bi, J Huang, Y Tang, S Du… - International journal of …, 2020 - Taylor & Francis
Exosomes are nano-sized small extracellular vesicles secreted by cells, carrying nucleic
acids, proteins, lipids and other bioactive substances to play a role in the body's …

Recent progress in targeted delivery vectors based on biomimetic nanoparticles

L Chen, W Hong, W Ren, T Xu, Z Qian… - Signal transduction and …, 2021 - nature.com
Over the past decades, great interest has been given to biomimetic nanoparticles (BNPs)
since the rise of targeted drug delivery systems and biomimetic nanotechnology. Biological …

Overview and update on extracellular vesicles: considerations on exosomes and their application in modern medicine

MA Di Bella - Biology, 2022 - mdpi.com
Simple Summary Exosomes are a subpopulation of extracellular vesicles, nanosized
particles, lipid bilayer-enclosed, naturally secreted from cells after the fusion of intracellular …

Quantification of protein cargo loading into engineered extracellular vesicles at single‐vesicle and single‐molecule resolution

AM Silva, E Lázaro‐Ibáñez… - Journal of …, 2021 - Wiley Online Library
Abstract Extracellular Vesicles (EVs) have been intensively explored for therapeutic delivery
of proteins. However, methods to quantify cargo proteins loaded into engineered EVs are …

Promising applications of tumor spheroids and organoids for personalized medicine

Z Gilazieva, A Ponomarev, C Rutland, A Rizvanov… - Cancers, 2020 - mdpi.com
Simple Summary Presently, the investigation of the tumor is carried out using different
models. One of the promising areas is the creation of 3D tumor models, such as spheroids …

[HTML][HTML] Isolation and analysis methods of extracellular vesicles (EVs)

Z Zhao, H Wijerathne, AK Godwin… - Extracellular vesicles and …, 2021 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) have been recognized as an evolving biomarker within the
liquid biopsy family. While carrying both host cell proteins and different types of RNAs, EVs …

Nanomaterials for the treatment and diagnosis of Alzheimer's disease: an overview

M Bilal, M Barani, F Sabir, A Rahdar, GZ Kyzas - NanoImpact, 2020 - Elsevier
Alzheimer's disease (AD) is a chronic neurodegenerative disorder associated with
dementia. To overcome the limitations of diagnosis and treatment nanotechnology research …

Nanoalgosomes: Introducing extracellular vesicles produced by microalgae

G Adamo, D Fierli, DP Romancino… - Journal of …, 2021 - Wiley Online Library
Cellular, inter‐organismal and cross kingdom communication via extracellular vesicles
(EVs) is intensively studied in basic science with high expectation for a large variety of bio …

BDNF and pro-BDNF in serum and exosomes in major depression: Evolution after antidepressant treatment

T Gelle, RA Samey, B Plansont, B Bessette… - Progress in Neuro …, 2021 - Elsevier
Background The study of clinically related biological indicators in Major Depression (MD) is
important. The Brain Derived Neurotrophic Factor (BDNF) appears to play an important role …

[HTML][HTML] The role of extracellular vesicles in the physiological and pathological regulation of the blood–brain barrier

S Busatto, G Morad, P Guo, MA Moses - FASEB BioAdvances, 2021 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are a subclass of biological nanoparticles secreted by most cell
types. Once secreted, EVs can travel long distances to deliver their content to target cells …