Recent advances in metabolic engineering of Saccharomyces cerevisiae: new tools and their applications

J Lian, S Mishra, H Zhao - Metabolic engineering, 2018 - Elsevier
Metabolic engineering aims to develop efficient cell factories by rewiring cellular
metabolism. As one of the most commonly used cell factories, Saccharomyces cerevisiae …

Valorization of industrial waste and by-product streams via fermentation for the production of chemicals and biopolymers

AA Koutinas, A Vlysidis, D Pleissner… - Chemical Society …, 2014 - pubs.rsc.org
The transition from a fossil fuel-based economy to a bio-based economy necessitates the
exploitation of synergies, scientific innovations and breakthroughs, and step changes in the …

The quest for sustainable polyesters–insights into the future

C Vilela, AF Sousa, AC Fonseca, AC Serra… - Polymer …, 2014 - pubs.rsc.org
Polyesters from renewable resources are an expanding area with a burgeoning scientific
activity, nevertheless little has been reviewed about this particular class of polymers. The …

Advances in metabolic engineering of yeast Saccharomyces cerevisiae for production of chemicals

I Borodina, J Nielsen - Biotechnology journal, 2014 - Wiley Online Library
Yeast Saccharomyces cerevisiae is an important industrial host for production of enzymes,
pharmaceutical and nutraceutical ingredients and recently also commodity chemicals and …

Metabolic engineering in the biotechnological production of organic acids in the tricarboxylic acid cycle of microorganisms: advances and prospects

X Yin, J Li, H Shin, G Du, L Liu, J Chen - Biotechnology advances, 2015 - Elsevier
Organic acids, which are chemically synthesized, are also natural intermediates in the
metabolic pathways of microorganisms, among which the tricarboxylic acid (TCA) cycle is …

DCEO biotechnology: tools to design, construct, evaluate, and optimize the metabolic pathway for biosynthesis of chemicals

X Chen, C Gao, L Guo, G Hu, Q Luo, J Liu… - Chemical …, 2018 - ACS Publications
Chemical synthesis is a well established route for producing many chemicals on a large
scale, but some drawbacks still exist in this process, such as unstable intermediates …

Recent advances in microbial production of fuels and chemicals using tools and strategies of systems metabolic engineering

C Cho, SY Choi, ZW Luo, SY Lee - Biotechnology advances, 2015 - Elsevier
The advent of various systems metabolic engineering tools and strategies has enabled more
sophisticated engineering of microorganisms for the production of industrially useful fuels …

Current advance in biological production of short-chain organic acid

L Sun, M Gong, X Lv, Z Huang, Y Gu, J Li, G Du… - Applied Microbiology …, 2020 - Springer
As natural metabolites, organic acids have been widely applied in food, pharmaceutical, and
bio-based materials industries. Particularly, the short-chain organic acids, including C2, C3 …

Genome-scale modeling of yeast: chronology, applications and critical perspectives

H Lopes, I Rocha - FEMS yeast research, 2017 - academic.oup.com
Over the last 15 years, several genome-scale metabolic models (GSMMs) were developed
for different yeast species, aiding both the elucidation of new biological processes and the …

Metabolic Engineering and Adaptive Evolution for Efficient Production of l-Lactic Acid in Saccharomyces cerevisiae

P Zhu, R Luo, Y Li, X Chen - Microbiology Spectrum, 2022 - Am Soc Microbiol
ABSTRACT l-Lactic acid (LA) is a three-carbon hydroxycarboxylic acid with extensive
applications in food, cosmetic, agricultural, pharmaceutical, and bioplastic industries …