Cannabinoids: therapeutic use in clinical practice

C Pagano, G Navarra, L Coppola, G Avilia… - International journal of …, 2022 - mdpi.com
Medical case reports suggest that cannabinoids extracted from Cannabis sativa have
therapeutic effects; however, the therapeutic employment is limited due to the psychotropic …

The endocannabinoid system: a potential target for the treatment of various diseases

H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

What is new in the pathophysiology of acne, an overview

B Dréno - Journal of the European Academy of Dermatology …, 2017 - Wiley Online Library
Acne is a chronic inflammatory disease of the pilosebaceous unit. Its pathophysiology
includes hyperseborrhoea, abnormal follicular keratinization and Propionibacterium acnes …

From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology

A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

The gut‐skin axis in health and disease: a paradigm with therapeutic implications

CA O'Neill, G Monteleone, JT McLaughlin, R Paus - Bioessays, 2016 - Wiley Online Library
As crucial interface organs gut and skin have much in common. Therefore it is unsurprising
that several gut pathologies have skin co‐morbidities. Nevertheless, the reason for this …

Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects

EB Russo - British journal of pharmacology, 2011 - Wiley Online Library
Tetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964,
when Raphael Mechoulam isolated and synthesized it. More recently, the synergistic …

Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C (ut) annabinoid” System

KF Tóth, D Ádám, T Bíró, A Oláh - Molecules, 2019 - mdpi.com
The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes

A Oláh, BI Tóth, I Borbíró, K Sugawara… - The Journal of …, 2014 - Am Soc Clin Investig
The endocannabinoid system (ECS) regulates multiple physiological processes, including
cutaneous cell growth and differentiation. Here, we explored the effects of the major …

Sebaceous immunobiology-skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations

CC Zouboulis, T Coenye, L He, K Kabashima… - Frontiers in …, 2022 - frontiersin.org
This review presents several aspects of the innovative concept of sebaceous
immunobiology, which summarizes the numerous activities of the sebaceous gland …

Therapeutic potential of cannabidiol (CBD) for skin health and disorders

SM Baswan, AE Klosner, K Glynn… - Clinical, cosmetic and …, 2020 - Taylor & Francis
Though there is limited research confirming the purported topical benefits of cannabinoids, it
is certain that cutaneous biology is modulated by the human endocannabinoid system …