Sepsis acute kidney injury (SAKI) is a common complication of sepsis, accounting for 26–
50% of all acute kidney injury (AKI). AKI is an independent risk factor for increased mortality …

Acute Kidney Injury (AKI) complicates up to 10% of hospital admissions substantially
increasing patient morbidity and mortality. Experimental evidence supports that AKI initiation …

Background: Acute kidney injury (AKI) remains a major global public health concern due to
its high morbidity and mortality. The progression from AKI to chronic kidney disease (CKD) …

Angiogenesis and immunosuppression are closely related pathophysiologic processes.
Widely prescribed in malignant tumor and proliferative retinal lesions, VEGF signaling …

Acute kidney injury (AKI) is a world-wide health problem and linked with increased risk of
morbidity/mortality in hospitalized patients and its incidence has been on the rise in the last …

Despite significant advances in surgical technique and strategies for tissue/organ protection,
cardiac surgery involving cardiopulmonary bypass is a profound stressor on the human …

Background Alterations in serum creatinine levels delay the identification of severe cardiac
surgery‐associated acute kidney injury. To provide timely diagnosis, novel predictive tools …

Cardiopulmonary bypass (CPB) may trigger organs damage, including kidney injury, due to
a massive cytokine release. In this observational, prospective study, we analyzed the …

Objective Patients with cardiac surgery–associated acute kidney injury are at risk of renal
replacement therapy and in-hospital death. We aimed to develop and validate a novel …

Durable and temporary mechanical circulatory support (MCS) use is growing for a range of
cardiovascular indications. Kidney dysfunction is common in people evaluated for or …