[HTML][HTML] Emerging therapeutic strategies of different immunotherapy approaches combined with PD-1/PD-L1 blockade in cervical cancer

Y Ge, Y Zhang, KN Zhao, H Zhu - Drug Design, Development and …, 2022 - ncbi.nlm.nih.gov
Currently, therapeutic methods for advanced and recurrent cervical cancer patients are
limited and unsatisfactory. Immunotherapy is a promising approach for cancer treatment …

S-Nitrosylation in tumor microenvironment

V Sharma, V Fernando, J Letson, Y Walia… - International journal of …, 2021 - mdpi.com
S-nitrosylation is a selective and reversible post-translational modification of protein thiols by
nitric oxide (NO), which is a bioactive signaling molecule, to exert a variety of effects. These …

Prevotella as the hub of the cervicovaginal microbiota affects the occurrence of persistent human papillomavirus infection and cervical lesions in women of …

B Dong, Y Huang, H Cai, Y Chen, Y Li… - Journal of Medical …, 2022 - Wiley Online Library
There is evidence that coinfection of cervicovaginal high‐risk human papillomavirus (HR‐
HPV) and bacteria is common in women of childbearing age. However, the relationship …

Prior antibiotic administration disrupts anti-PD-1 responses in advanced gastric cancer by altering the gut microbiome and systemic immune response

CG Kim, JY Koh, SJ Shin, JH Shin, M Hong… - Cell Reports …, 2023 - cell.com
Evidence on whether prior antibiotic (pATB) administration modulates outcomes of
programmed cell death protein-1 (PD-1) inhibitors in advanced gastric cancer (AGC) is …

Potential role of vaginal microbiota in ovarian cancer carcinogenesis, progression and treatment

X Zhao, Z Liu, T Chen - Pharmaceutics, 2023 - mdpi.com
Ovarian cancer represents one of the most challenging gynecologic cancers which still has
numerous unknowns on the underlying pathogenesis. In addition to the verified contributors …

Multi-omics data integration reveals metabolome as the top predictor of the cervicovaginal microenvironment

NA Bokulich, P Łaniewski, A Adamov… - PLoS computational …, 2022 - journals.plos.org
Emerging evidence suggests that host-microbe interaction in the cervicovaginal
microenvironment contributes to cervical carcinogenesis, yet dissecting these complex …

Cervicovaginal microbiome factors in clearance of human papillomavirus infection

W Dai, H Du, S Li, R Wu - Frontiers in Oncology, 2021 - frontiersin.org
Persistent high-risk human papillomavirus (hrHPV) infection is the highest risk to cervical
cancer which is the fourth most common cancer in women worldwide. A growing body of …

The interaction between the microbiome and tumors

Y Zong, Y Zhou, B Liao, M Liao, Y Shi, Y Wei… - Frontiers in Cellular …, 2021 - frontiersin.org
Cancer is a significant global health problem and is characterized by a consistent increase
in incidence and mortality rate. Deciphering the etiology and risk factors are essential parts …

The association of cervicovaginal Langerhans cells with clearance of human papillomavirus

W Dai, L Gui, H Du, S Li, R Wu - Frontiers in immunology, 2022 - frontiersin.org
Human papillomavirus (HPV) clearance is important in eliminating cervical cancer which
contributes to high morbidity and mortality in women. Nevertheless, it remains largely …

The microbiota as a modulator of mucosal inflammation and HIV/HPV pathogenesis: from association to causation

E Moreno, R Ron, S Serrano-Villar - Frontiers in Immunology, 2023 - frontiersin.org
Although the microbiota has largely been associated with the pathogenesis of viral
infections, most studies using omics techniques are correlational and hypothesis …