Residual inflammation and viral reservoirs: alliance against an HIV cure

M Massanella, R Fromentin… - Current Opinion in HIV …, 2016 - journals.lww.com
Residual inflammation and viral reservoirs: alliance against... : Current Opinion in HIV and
AIDS Residual inflammation and viral reservoirs: alliance against an HIV cure : Current …

The development and application of matrix assisted laser desorption electrospray ionization: The teenage years

M Caleb Bagley, KP Garrard… - Mass Spectrometry …, 2023 - Wiley Online Library
In the past 15 years, ambient ionization techniques have witnessed a significant incursion
into the field of mass spectrometry imaging, demonstrating their ability to provide …

HIV DNA persists in hepatocytes in people with HIV-hepatitis B co-infection on antiretroviral therapy

JM Zerbato, A Avihingsanon, KP Singh, W Zhao… - …, 2023 - thelancet.com
Background HIV can infect multiple cells in the liver including hepatocytes, Kupffer cells and
infiltrating T cells, but whether HIV can persist in the liver in people with HIV (PWH) on …

Biologically relevant heterogeneity: metrics and practical insights

A Gough, AM Stern, J Maier, T Lezon… - … Life Sciences R&D, 2017 - journals.sagepub.com
Heterogeneity is a fundamental property of biological systems at all scales that must be
addressed in a wide range of biomedical applications, including basic biomedical research …

Simian immunodeficiency virus persistence in cellular and anatomic reservoirs in antiretroviral therapy-suppressed infant rhesus macaques

M Mavigner, J Habib, C Deleage, E Rosen… - Journal of …, 2018 - Am Soc Microbiol
Worldwide, nearly two million children are infected with human immunodeficiency virus
(HIV), with breastfeeding accounting for the majority of contemporary HIV transmissions …

Heterogeneous antiretroviral drug distribution and HIV/SHIV detection in the gut of three species

CG Thompson, EP Rosen, HMA Prince… - Science translational …, 2019 - science.org
HIV replication within tissues may increase in response to a reduced exposure to
antiretroviral drugs. Traditional approaches to measuring drug concentrations in tissues are …

Understanding patterns of HIV multi-drug resistance through models of temporal and spatial drug heterogeneity

AF Feder, KN Harper, CJ Brumme, PS Pennings - Elife, 2021 - elifesciences.org
Triple-drug therapies have transformed HIV from a fatal condition to a chronic one. These
therapies should prevent HIV drug resistance evolution, because one or more drugs …

[HTML][HTML] HIV persistence in lymph nodes

R Banga, O Munoz, M Perreau - Current Opinion in HIV and AIDS, 2021 - journals.lww.com
HIV persistence in blood and distinct body compartments despite long-standing and potent
therapy is one of the major barriers to a cure. Given that the HIV reservoir is established …

The lymph node reservoir: physiology, HIV infection, and antiretroviral therapy

EMB Scholz, ADM Kashuba - Clinical Pharmacology & …, 2021 - Wiley Online Library
Despite advances in treatment, finding a cure for HIV remains a top priority. Chronic HIV
infection is associated with increased risk of comorbidities, such as diabetes and …

Proviral latency, persistent human immunodeficiency virus infection, and the development of latency reversing agents

DM Margolis, NM Archin - The Journal of infectious diseases, 2017 - academic.oup.com
Quiescent proviral genomes that persist during human immunodeficiency virus type 1 (HIV-
1) infection despite effective antiretroviral therapy (ART) can fuel rebound viremia after ART …