The multiscale physics of cilia and flagella

W Gilpin, MS Bull, M Prakash - Nature Reviews Physics, 2020 - nature.com
Cilia and flagella are fundamental units of motion in cellular biology. These beating, hair-like
organelles share a common basic structure but maintain widely varying functions in systems …

Transient receptor potential channels: current perspectives on evolution, structure, function and nomenclature

NJ Himmel, DN Cox - Proceedings of the Royal Society …, 2020 - royalsocietypublishing.org
The transient receptor potential superfamily of ion channels (TRP channels) is widely
recognized for the roles its members play in sensory nervous systems. However, the …

[HTML][HTML] A neuropeptidergic circuit gates selective escape behavior of Drosophila larvae

BN Imambocus, F Zhou, A Formozov, A Wittich… - Current Biology, 2022 - cell.com
Animals display selective escape behaviors when faced with environmental threats.
Selection of the appropriate response by the underlying neuronal network is key to …

Reafference and the origin of the self in early nervous system evolution

G Jékely, P Godfrey-Smith… - … Transactions of the …, 2021 - royalsocietypublishing.org
Discussions of the function of early nervous systems usually focus on a causal flow from
sensors to effectors, by which an animal coordinates its actions with exogenous changes in …

Whole-body integration of gene expression and single-cell morphology

HM Vergara, C Pape, KI Meechan, V Zinchenko… - Cell, 2021 - cell.com
Animal bodies are composed of cell types with unique expression programs that implement
their distinct locations, shapes, structures, and functions. Based on these properties, cell …

The role of motile cilia in the development and physiology of the nervous system

C Ringers, EW Olstad… - … Transactions of the …, 2020 - royalsocietypublishing.org
Motile cilia are miniature, whip-like organelles whose beating generates a directional fluid
flow. The flow generated by ciliated epithelia is a subject of great interest, as defective ciliary …

Elementary nervous systems

D Arendt - … Transactions of the Royal Society B, 2021 - royalsocietypublishing.org
The evolutionary origin of the nervous system has been a matter of long-standing debate.
This is due to the different perspectives taken. Earlier studies addressed nervous system …

The cilium as a force sensor− myth versus reality

R R. Ferreira, H Fukui, R Chow, A Vilfan… - Journal of cell …, 2019 - journals.biologists.com
Cells need to sense their mechanical environment during the growth of developing tissues
and maintenance of adult tissues. The concept of force-sensing mechanisms that act …

Diversity of cilia-based mechanosensory systems and their functions in marine animal behaviour

LA Bezares-Calderón, J Berger… - … Transactions of the …, 2020 - royalsocietypublishing.org
Sensory cells that detect mechanical forces usually have one or more specialized cilia.
These mechanosensory cells underlie hearing, proprioception or gravity sensation. To date …

What is it like to be a choanoflagellate? Sensation, processing and behavior in the closest unicellular relatives of animals

N Ros-Rocher, T Brunet - Animal Cognition, 2023 - Springer
All animals evolved from a single lineage of unicellular precursors more than 600 million
years ago. Thus, the biological and genetic foundations for animal sensation, cognition and …