Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

The stealth effect plays a central role on capacitating nanomaterials for drug delivery
applications through improving the pharmacokinetics such as blood circulation …

Ischemic heart disease (IHD) is the leading cause of disability and mortality worldwide.
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …

Thrombotic cerebro-cardiovascular diseases are the leading causes of disability and death
worldwide. However, current drug therapeutics are compromised by narrow therapeutic …

This study shows that the supramolecular arrangement of proteins in nanoparticle structures
predicts nanoparticle accumulation in neutrophils in acute lung inflammation (ALI). We …

Red blood cells (RBCs) constitute a unique drug delivery system as a biologic or hybrid
carrier capable of greatly enhancing pharmacokinetics, altering pharmacodynamics (for …

Modification of nano/micro-particle physical parameters (eg size, shape, surface charge) has
proven to be an effective method to enhance their delivery abilities. Recently, advances in …

Intravascular drug delivery technologies majorly utilize spherical nanoparticles as carrier
vehicles. Their targets are often at the blood vessel wall or in the tissue beyond the wall …

Red blood cell (RBC) hitchhiking is a method of drug delivery that can increase drug
concentration in target organs by orders of magnitude. In RBC hitchhiking, drug-loaded …

In the drug delivery field, there is beyond doubt that the shape of micro-and nanoparticles
(M&NPs) critically affects their biological fate. Herein, following an introduction describing …