The pathogenesis of dengue virus infection is attributed to complex interplay between virus,
host genes and host immune response. Host factors such as antibody-dependent …

Mortality from severe dengue is low, but the economic and resource burden on health
services remains substantial in endemic settings. Unfortunately, progress towards …

Dengue is an arboviral infection that is hyperendemic in tropical and subtropical climates.
Clinical manifestations of dengue can range from asymptomatic infection to severe infection …

For dengue viruses 1 to 4 (DENV1-4), a specific range of antibody titer has been shown to
enhance viral replication in vitro and severe disease in animal models. Although suspected …

Background Dengue is an arboviral disease caused by dengue virus. Symptomatic dengue
infection causes a wide range of clinical manifestations, from mild dengue fever (DF) to …

Infection with any of the 4 dengue virus serotypes results in a diverse range of symptoms,
from mild undifferentiated fever to life-threatening hemorrhagic fever and shock. Given that …

Dengue is a major health threat and the number of symptomatic infections caused by the
four dengue serotypes is estimated to be 96 million with annually around 10,000 deaths …

Dengue is the leading mosquito-borne viral illness infecting humans. Owing to the
circulation of multiple serotypes, global expansion of the disease and recent gains in …

Opinion statement Dengue viruses (DENV) continue to circulate worldwide, resulting in a
significant burden on human health. There are four antigenically distinct serotypes of DENV …

The four dengue virus serotypes (DENV1 to DENV4) are mosquito-borne flaviviruses that
cause up to~ 100 million cases of dengue annually worldwide. Severe disease is thought to …