Management of Crohn disease: a review

K Cushing, PDR Higgins - Jama, 2021 - jamanetwork.com
Importance Crohn disease, a chronic gastrointestinal inflammatory disease, is increasing in
incidence and prevalence in many parts of the world. Uncontrolled inflammation leads to …

ACG clinical guideline: preventive care in inflammatory bowel disease

FA Farraye, GY Melmed, GR Lichtenstein… - Official journal of the …, 2017 - journals.lww.com
Recent data suggest that inflammatory bowel disease (IBD) patients do not receive
preventive services at the same rate as general medical patients. Patients with IBD often …

Environmental risk factors for inflammatory bowel disease

N Singh, CN Bernstein - United European gastroenterology …, 2022 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic, progressive immune‐mediated inflammatory
condition of the gastrointestinal tract. Environmental risk factors play a role in developing …

Location is important: differentiation between ileal and colonic Crohn's disease

R Atreya, B Siegmund - Nature Reviews Gastroenterology & …, 2021 - nature.com
Crohn's disease can affect any part of the gastrointestinal tract; however, current European
and national guidelines worldwide do not differentiate between small-intestinal and colonic …

Effect of lifestyle factors on outcomes in patients with inflammatory bowel diseases

JJ Rozich, A Holmer, S Singh - … journal of the American College of …, 2020 - journals.lww.com
Various lifestyle factors including physical activity and obesity, stress, sleep, and smoking
may modify the risk of developing inflammatory bowel diseases (IBDs). In patients with …

Personalizing treatment in IBD: hype or reality in 2020? Can we predict response to anti-TNF?

R Atreya, MF Neurath, B Siegmund - Frontiers in medicine, 2020 - frontiersin.org
The advent of anti-TNF agents as the first approved targeted therapy in the treatment of
inflammatory bowel disease (IBD) patients has made a major impact on our existing …

Smoking in inflammatory bowel disease: impact on disease course and insights into the aetiology of its effect

GC Parkes, K Whelan, JO Lindsay - Journal of Crohn's and …, 2014 - academic.oup.com
The chronic intestinal inflammation that characterises Crohn's disease and ulcerative colitis
arises from a complex interplay between host genotype, the immune system, and the …

Increased mortality rates with prolonged corticosteroid therapy when compared with antitumor necrosis factor-α-directed therapy for inflammatory bowel disease

JD Lewis, FI Scott, CM Brensinger, JA Roy… - Official journal of the …, 2018 - journals.lww.com
OBJECTIVES: Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel
diseases (IBD) that compromise quality of life and may increase mortality. This study …

[HTML][HTML] Clinical characteristics and treatment of inflammatory bowel disease: a comparison of Eastern and Western perspectives

SJ Park, WH Kim, JH Cheon - World Journal of Gastroenterology …, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic, relapsing intestinal inflammatory disorder
with unidentified causes. Both environmental factors and genetic aspects are believed to be …

Relapse after withdrawal from anti‐TNF therapy for inflammatory bowel disease: an observational study, plus systematic review and meta‐analysis

NA Kennedy, B Warner, EL Johnston… - Alimentary …, 2016 - Wiley Online Library
Background Infliximab and adalimumab have established roles in inflammatory bowel
disease (IBD) therapy. UK regulators mandate reassessment after 12 months' anti‐TNF …