Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options
JCO Sardi, L Scorzoni, T Bernardi… - Journal of medical …, 2013 - microbiologyresearch.org
The incidence of fungal infections has increased significantly, so contributing to morbidity
and mortality. This is caused by an increase in antimicrobial resistance and the restricted …
and mortality. This is caused by an increase in antimicrobial resistance and the restricted …
[HTML][HTML] Morbidity and mortality of candidaemia in Europe: an epidemiologic meta-analysis
Objectives Candidaemia is a serious hazard to hospitalized patients, but European
epidemiological data are restricted to national studies focusing on Northern Europe …
epidemiological data are restricted to national studies focusing on Northern Europe …
Genetic control of Candida albicans biofilm development
JS Finkel, AP Mitchell - Nature Reviews Microbiology, 2011 - nature.com
Candida species cause frequent infections owing to their ability to form biofilms—surface-
associated microbial communities—primarily on implanted medical devices. Increasingly …
associated microbial communities—primarily on implanted medical devices. Increasingly …
Epidemiology of invasive mycoses in North America
MA Pfaller, DJ Diekema - Critical reviews in microbiology, 2010 - Taylor & Francis
The incidence of invasive mycoses is increasing, especially among patients who are
immunocompromised or hospitalized with serious underlying diseases. Such infections may …
immunocompromised or hospitalized with serious underlying diseases. Such infections may …
Epidemiology of Candida species infections in critically ill non-immunosuppressed patients
P Eggimann, J Garbino, D Pittet - The Lancet infectious diseases, 2003 - thelancet.com
A substantial proportion of patients become colonised with Candida spp during hospital
stay, but only few subsequently develop severe infection. Clinical signs of severe infection …
stay, but only few subsequently develop severe infection. Clinical signs of severe infection …
Candida Biofilms: an Update
G Ramage, SP Saville, DP Thomas… - Eukaryotic cell, 2005 - Am Soc Microbiol
Our classical perception of microorganisms as unicellular life forms is almost entirely based
on the pure-culture mode of growth; since microbial suspensions can be diluted to a single …
on the pure-culture mode of growth; since microbial suspensions can be diluted to a single …
Dispersion as an Important Step in the Candida albicans Biofilm Developmental Cycle
Biofilms are dynamic microbial communities in which transitions between planktonic and
sessile modes of growth occur interchangeably in response to different environmental cues …
sessile modes of growth occur interchangeably in response to different environmental cues …
Engineered Control of Cell Morphology In Vivo Reveals Distinct Roles for Yeast and Filamentous Forms of Candida albicans during Infection
SP Saville, AL Lazzell, C Monteagudo… - Eukaryotic …, 2003 - Am Soc Microbiol
It is widely assumed that the ability of Candida albicans to switch between different
morphologies is required for pathogenesis. However, most virulence studies have used …
morphologies is required for pathogenesis. However, most virulence studies have used …
Candida biofilms on implanted biomaterials: a clinically significant problem
G Ramage, JP Martínez, JL López-Ribot - FEMS yeast research, 2006 - academic.oup.com
In recent years there has been an increasing appreciation that microbial biofilms are
ubiquitous, which has resulted in a number of studies on infectious diseases from a biofilm …
ubiquitous, which has resulted in a number of studies on infectious diseases from a biofilm …
Quorum sensing and social networking in the microbial world
S Atkinson, P Williams - Journal of the Royal Society …, 2009 - royalsocietypublishing.org
For many years, bacterial cells were considered primarily as selfish individuals, but, in
recent years, it has become evident that, far from operating in isolation, they coordinate …
recent years, it has become evident that, far from operating in isolation, they coordinate …