Understanding the physics of glass formation remains one of the major unsolved challenges
of condensed matter science. As a material solidifies into a glass, it exhibits a spectacular …

The size of a cell is determined by a combination of synthesis, self-assembly, incoming
matter and the balance of mechanical forces. Such processes operate at the single-cell …

During osmotic changes of their environment, cells actively regulate their volume and
plasma membrane tension that can passively change through osmosis. How tension and …

Cells alter their mechanical properties in response to their local microenvironment; this plays
a role in determining cell function and can even influence stem cell fate. Here, we identify a …

Control of the structure and function of three-dimensional multicellular tissues depends
critically on the spatial and temporal coordination of cellular physical properties, yet the …

The mechanical phenotype of a cell is an inherent biophysical marker of its state and
function, with many applications in basic and applied biological research. Microfluidics …

Molecular motors in cells typically produce highly directed motion; however, the aggregate,
incoherent effect of all active processes also creates randomly fluctuating forces, which drive …

Current measurements of the biomechanical properties of cells require physical contact with
cells or lack subcellular resolution. Here we developed a label-free microscopy technique …

The cytoplasm is the largest part of the cell by volume and hence its rheology sets the rate at
which cellular shape changes can occur. Recent experimental evidence suggests that …

Combining extensive single particle tracking microscopy data of endogenous lipid granules
in living fission yeast cells with analytical results we show evidence for anomalous diffusion …