[HTML][HTML] New insights regarding genetic aspects of childhood obesity: a minireview

CO Mǎrginean, C Mǎrginean, LE Meliţ - Frontiers in pediatrics, 2018 - frontiersin.org
Introduction: Childhood obesity is occurring at alarming rates in both developed and
developing countries.“Obesogenic” environmental factors must be associated with variants …

[HTML][HTML] Prebiotics, probiotics, and synbiotics—a research hotspot for pediatric obesity

R Borka Balas, LE Meliț, A Lupu, VV Lupu… - Microorganisms, 2023 - mdpi.com
Childhood obesity is a major public health problem worldwide with an increasing
prevalence, associated not only with metabolic syndrome, insulin resistance, hypertension …

[HTML][HTML] Early inflammatory status related to pediatric obesity

CO Mărginean, LE Meliţ, DV Ghiga… - Frontiers in …, 2019 - frontiersin.org
Background: Obese individuals are often in a chronic inflammatory condition due to the
malfunction of immune-related activities in the adipose tissue, involving a transient …

The adipokines and inflammatory status in the era of pediatric obesity

CO Mărginean, LE Meliţ, A Huțanu, DV Ghiga… - Cytokine, 2020 - Elsevier
Introduction Obesity is associated with a chronic inflammation due to the deficiency in
immune activity related to adipose tissue. A wide-spectrum of pro-inflammatory cytokines …

[HTML][HTML] The FTO rs9939609 and LEPR rs1137101 mothers–newborns gene polymorphisms and maternal fat mass index effects on anthropometric characteristics in …

C Marginean, CO Marginean, M Iancu, LE Melit… - Medicine, 2016 - journals.lww.com
The aim of this study was to assess the impact of mothers' and newborns' fat mass and
obesity-associated gene (FTO) rs9939609 and leptin receptor (LEPR) rs1137101 gene …

Association of interleukin‐6 polymorphisms with obesity or metabolic traits in young Mexican‐Americans

K Boeta‐Lopez, J Duran, D Elizondo… - Obesity science & …, 2018 - Wiley Online Library
Objective The objective of the study is to investigate the association of interleukin‐6 (IL6)
promoter single‐nucleotide polymorphisms rs1800797 (‐597 G/A) and rs1800796 (‐572 …

[HTML][HTML] The usefulness of inflammatory biomarkers in diagnosing child and adolescent's gastritis: STROBE compliant article

LE Meliţ, MO Mărginean, S Mocan, CO Mărginean - Medicine, 2019 - journals.lww.com
Neutrophil to lymphocyte ratio (NLR) is a simple, noninvasive, inexpensive inflammatory
marker that can useful in the assessment of inflammatory activity, especially in pediatric …

[HTML][HTML] The role of TGF-β1 869 T> C and PPAR γ2 34 C> G polymorphisms, fat mass, and anthropometric characteristics in predicting childhood obesity at birth: a …

C Marginean, CO Marginean, M Iancu, B Szabo… - Medicine, 2016 - journals.lww.com
This study proposed to establish a correlation between the risk score for child obesity and
anthropometric, genetic, and bioimpedance characteristics in mothers and newborns, and to …

[HTML][HTML] Dietary acid load and its interaction with IGF1 (rs35767 and rs7136446) and IL6 (rs1800796) polymorphisms on metabolic traits among postmenopausal …

SY Lim, YM Chan, V Ramachandran, ZM Shariff… - Nutrients, 2021 - mdpi.com
The objective of this study was to explore the effects of dietary acid load (DAL) and IGF1 and
IL6 gene polymorphisms and their potential diet–gene interactions on metabolic traits. A …

[HTML][HTML] Systemic inflammatory status–a bridge between gestational weight gain and neonatal outcomes (STROBE-compliant article)

C Rugină, CO Mărginean, LE Meliţ, A Huţanu… - Medicine, 2021 - journals.lww.com
Systemic inflammatory status – a bridge between gestational... : Medicine Systemic
inflammatory status – a bridge between gestational weight gain and neonatal outcomes (STROBE-compliant …