[HTML][HTML] Multi-omics characterization of the monkeypox virus infection
Multiple omics analyzes of Vaccinia virus (VACV) infection have defined molecular
characteristics of poxvirus biology. However, little is known about the monkeypox (mpox) …
characteristics of poxvirus biology. However, little is known about the monkeypox (mpox) …
Mpox virus infection and drug treatment modelled in human skin organoids
Mpox virus (MPXV) primarily infects human skin to cause lesions. Currently, robust models
that recapitulate skin infection by MPXV are lacking. Here we demonstrate that human …
that recapitulate skin infection by MPXV are lacking. Here we demonstrate that human …
[HTML][HTML] Clinical and laboratory diagnosis of monkeypox (mpox): Current status and future directions
The emergence and rapid spread of the monkeypox virus (MPXV) to non-endemic countries
has brought this once obscure pathogen to the forefront of global public health. Given the …
has brought this once obscure pathogen to the forefront of global public health. Given the …
Human skin-on-a-chip for mpox pathogenesis studies and preclinical drug evaluation
Timely intervention of preventative and therapeutic measures abated a 2022 mpox global
outbreak. However, the high transmissibility and unique pathological characteristics of mpox …
outbreak. However, the high transmissibility and unique pathological characteristics of mpox …
[HTML][HTML] A monoclonal antibody produced in glycoengineered plants potently neutralizes monkeypox virus
The 2022 global outbreaks of monkeypox virus (MPXV) and increased human-to-human
transmission calls for the urgent development of countermeasures to protect people who …
transmission calls for the urgent development of countermeasures to protect people who …
Virological characterization of the 2022 outbreak‐causing monkeypox virus using human keratinocytes and colon organoids
Y Watanabe, I Kimura, R Hashimoto… - Journal of Medical …, 2023 - Wiley Online Library
The outbreak‐causing monkeypox virus of 2022 (2022 MPXV) is classified as a clade IIb
strain and phylogenetically distinct from prior endemic MPXV strains (clades I or IIa) …
strain and phylogenetically distinct from prior endemic MPXV strains (clades I or IIa) …
[HTML][HTML] Role of direct sexual contact in human transmission of Monkeypox virus, Italy
The 2022 global mpox outbreak was driven by human-to-human transmission, but modes of
transmission by sexual relationship versus sexual contact remain unclear. We evaluated …
transmission by sexual relationship versus sexual contact remain unclear. We evaluated …
Utilizing non‐human primate models to combat recent COVID‐19/SARS‐CoV‐2 and viral infectious disease outbreaks
T Kwon - Journal of Medical Primatology, 2024 - Wiley Online Library
In recent times, global viral outbreaks and diseases, such as COVID‐19 (SARS‐CoV‐2),
Zika (ZIKV), monkeypox (MPOX), Ebola (EBOV), and Marburg (MARV), have been …
Zika (ZIKV), monkeypox (MPOX), Ebola (EBOV), and Marburg (MARV), have been …
[HTML][HTML] Machine Learning Analysis of RNA-Seq Data Identifies Key Gene Signatures and Pathways in Mpox Virus-Induced Gastrointestinal Complications Using …
M Rezapour, A Narayanan, MN Gurcan - International Journal of …, 2024 - mdpi.com
Mpox, caused by the Mpox virus (MPXV), emerged globally in 2022 with the Clade IIb strain,
presenting a critical public health challenge. While MPXV is primarily characterized by fever …
presenting a critical public health challenge. While MPXV is primarily characterized by fever …
[HTML][HTML] Mouse Models of Mayaro Virus
RB Rosa, EF de Castro, D de Oliveira Santos… - Viruses, 2023 - mdpi.com
Mayaro virus (MAYV), the etiologic agent of Mayaro fever, leads patients to severe myalgia
and arthralgia, which can have a major impact on public health in all the countries where the …
and arthralgia, which can have a major impact on public health in all the countries where the …