Opioids are a mainstay of acute pain management but can have many adverse effects,
contributing to problematic long-term use. Opioid tolerance (increased dose needed for …

Physicians, policymakers, and researchers are increasingly focused on finding ways to
decrease opioid use and overdose in the United States both of which have sharply …

Most patients who undergo surgical procedures experience acute postoperative pain, but
evidence suggests that less than half report adequate postoperative pain relief. Many …

Inadequate perioperative pain is, unfortunately, frequent, and has clinically relevant
consequences, including decreased patient satisfaction, delayed postoperative mobilization …

Background Over the past 2 decades, the use of intravenous ketamine infusions as a
treatment for chronic pain has increased dramatically, with wide variation in patient …

Background Ketamine infusions have been used for decades to treat acute pain, but a
recent surge in usage has made the infusions a mainstay of treatment in emergency …

Objectives: This review presents and discusses basic science findings and scientific
evidence generated within the last 2 decades in the field of acute postoperative pain …

Define chronic post-surgical pain (CPSP) according to the ICD-11 (International
Classification of Diseases, Eleventh Revision) classification and describe its impact on …

Background Inadequate pain management after surgery increases the risk of postoperative
complications and may predispose for chronic postsurgical pain. Perioperative ketamine …

Background Colorectal surgery is associated with considerable morbidity and prolonged
length of stay (LOS). Recognizing the need for improvement, we implemented an enhanced …