In eukaryotic organisms, noncoding RNAs (ncRNAs) have been implicated as important
regulators of multifaceted biological processes, including transcriptional, posttranscriptional …

Non-coding natural antisense transcripts (ncNATs) are regulatory RNA sequences that are
transcribed in the opposite direction to protein-coding or non-coding transcripts. These …

The parasite Trypanosoma brucei causes African sleeping sickness that is fatal to patients if
untreated. Parasite differentiation from a replicative slender form into a quiescent stumpy …

Leishmania is the causative agent of cutaneous and visceral diseases affecting millions of
individuals worldwide. Pseudouridine (Ψ), the most abundant modification on rRNA …

The regulation of protein synthesis is of extreme importance for cell survival in challenging
environmental conditions. Modulating gene expression at the level of translation allows a …

The parasite Trypanosoma brucei cycles between an insect and a mammalian host and is
the causative agent of sleeping sickness. Here, we performed high‐throughput mapping of …

Trypanosomatids are protozoan parasites that cause devastating vector-borne human
diseases. Gene expression regulation of these organisms depends on post-transcriptional …

Trypanosoma brucei, the parasite that causes sleeping sickness, cycles between an insect
and a mammalian host. However, the effect of RNA modifications such as …

Ribosomes, in general, are viewed as constitutive macromolecular machines where protein
synthesis takes place; however, this view has been recently challenged, supporting the …

Trypanosomatids are single-cell eukaryotic parasites. Unlike higher eukaryotes, they control
gene expression post-transcriptionally and not at the level of transcription initiation. This …