Digital histopathology by infrared spectroscopic imaging
R Bhargava - Annual Review of Analytical Chemistry, 2023 - annualreviews.org
Infrared (IR) spectroscopic imaging records spatially resolved molecular vibrational spectra,
enabling a comprehensive measurement of the chemical makeup and heterogeneity of …
enabling a comprehensive measurement of the chemical makeup and heterogeneity of …
Multimodal imaging based on vibrational spectroscopies and mass spectrometry imaging applied to biological tissue: a multiscale and multiomics review
Molecular imaging has the potential to unearth important spatial and temporal relationships
in biological systems, including intercellular signaling as well as environmentally-cued …
in biological systems, including intercellular signaling as well as environmentally-cued …
Infrared spectroscopic imaging advances as an analytical technology for biomedical sciences
TP Wrobel, R Bhargava - Analytical chemistry, 2018 - ACS Publications
Optical chemical imaging seeks to nondestructively acquire spatially resolved chemical
information without the use of labels or probes. The combination of vibrational mid-infrared …
information without the use of labels or probes. The combination of vibrational mid-infrared …
Quantum cascade laser-based infrared microscopy for label-free and automated cancer classification in tissue sections
C Kuepper, A Kallenbach-Thieltges, H Juette… - Scientific reports, 2018 - nature.com
A feasibility study using a quantum cascade laser-based infrared microscope for the rapid
and label-free classification of colorectal cancer tissues is presented. Infrared imaging is a …
and label-free classification of colorectal cancer tissues is presented. Infrared imaging is a …
Biomedical applications of mid-infrared quantum cascade lasers–a review
Mid-infrared spectroscopy has been applied to research in biology and medicine for more
than 20 years and conceivable applications have been identified. More recently, these …
than 20 years and conceivable applications have been identified. More recently, these …
Resolution limit in infrared chemical imaging
Chemical imaging combines the spatial specificity of optical microscopy with the spectral
selectivity of vibrational spectroscopy. Mid-infrared (IR) absorption imaging instruments are …
selectivity of vibrational spectroscopy. Mid-infrared (IR) absorption imaging instruments are …
SEM/EDS and optical microscopy analysis of microplastics
AV Girão - Handbook of Microplastics in the Environment, 2022 - Springer
Microplastics are threatening materials directly produced by anthropogenic activities or
resulting products of macroplastic degradation. Extended scientific research is being carried …
resulting products of macroplastic degradation. Extended scientific research is being carried …
Comparison of spectral and spatial denoising techniques in the context of High Definition FT-IR imaging hyperspectral data
P Koziol, MK Raczkowska, J Skibinska… - Scientific reports, 2018 - nature.com
The recent emergence of High Definition (HD) FT-IR and Quantum Cascade Laser (QCL)
Microscopes elevated the IR imaging field very close to clinical timescales. However, the …
Microscopes elevated the IR imaging field very close to clinical timescales. However, the …
Super-resolved 3D mapping of molecular orientation using vibrational techniques
When a sample has an anisotropic structure, it is possible to obtain additional information
controlling the polarization of incident light. With their straightforward instrumentation …
controlling the polarization of incident light. With their straightforward instrumentation …
Macromolecular orientation in biological tissues using a four-polarization method in FT-IR imaging
Fourier transform infrared spectroscopy has emerged as a powerful tool for tissue specimen
investigation. Its nondestructive and label-free character enables direct determination of …
investigation. Its nondestructive and label-free character enables direct determination of …